3II5

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 2.79

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-out 831 Type2 448 - 720 11
B Inactive DFGout BBAminus in-in none-out 831 Type2 449 - 721 16
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -        440        450        460 
mdrgshhhhh hsedrnrmkt lgrrdssdDW EIPDGQITVG 
       470        480        490        500 
QRIGSGSFGT VYKGKWHGDV AVKMLNVTAP TPQQLQAFKN 
       510        520        530        540 
EVGVLRKTRH VNILLFMGYS TKPQLAIVTQ WCEGSSLYHH 
       550        560        570        580 
LHIIETKFEM IKLIDIARQT AQGMDYLHAK SIIHRDLKSN 
       590        600        610        620 
NIFLHEDLTV KIGDFGLAtv ksrwsgshqf eqlsGSILWM 
       630        640        650        660 
APEVIRMQDK NPYSFQSDVY AFGIVLYELM TGQLPYSNIN 
       670        680        690        700 
NRDQIIFMVG RGYLSPDLSK VRSNCPKAMK RLMAECLKKK 
       710        720 
RDERPLFPQI LASIELLARS Lpkihr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None