2OIC

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in STU Type1 163 - 458 6
B Active DFGin BLAminus in-in in-in STU Type1 164 - 459 6
C None DFGin BLAminus in-in none-in STU Type1 161 - 458 10
D Active DFGin BLAminus in-in in-in STU Type1 161 - 459 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       169        179        189        199 
vSDTRFHSFS FYELKNVTNN FDERPISVGG NKMGEGGFGV 
       209        219        229        239 
VYKGYVNNTT VAVKKLaamv ditteeLKQQ FDQEIKVMAK 
       249        259        269        279 
CQHENLVELL GFSSDGDDLC LVYVYMPNGS LLDRLSCLDG 
       289        299        309        319 
TPPLSWHMRC KIAQGAANGI NFLHENHHIH RDIKSANILL 
       329        339        349        359 
DEAFTAKISD FGLARASEkf AQTVMTSRIV GTTAYMAPEA 
       369        379        389        399 
LRGEITPKSD IYSFGVVLLE IITGLPAVDE HREPQLLLDI 
       409        419        429        439 
KEEIEDEEKT IEDYIDKKMN DADSTSVEAM YSVASQCLHE 
       449        459 
KKNKRPDIKK VQQLLQEMTA s
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X342,X345,X346