2O8Y

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None in-out in-in No_ligand No_ligand 165 - 459 5
B Inactive None None in-out in-in No_ligand No_ligand 165 - 459 4
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       172        182        192        202 
trFHSFSFYE LKNVTNNFDE RPIsvgGNKM GEGGFGVVYK 
       212        222        232        242 
GYVNNTTVAV KKLaamvdit teelKQQFDQ EIKVMAKCQH 
       252        262        272        282 
ENLVELLGFS SDGDDLCLVY VYMPNGSLLD RLSCLDGTPP 
       292        302        312        322 
LSWHMRCKIA QGAANGINFL HENHHIHRDI KSANILLDEA 
       332        342        352        362 
FTAKISDFGL ARASekfaQT VMTSRIVGTT AYMAPEALRG 
       372        382        392        402 
EITPKSDIYS FGVVLLEIIT GLPAVDEHRE PQLLLDIKEE 
       412        422        432        442 
IEDEEKTIED YIDKKMNDAD STSVEAMYSV ASQCLHEKKN 
       452 
KRPDIKKVQQ LLQEMTAs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X342,X345