2FB8

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 215 Type1 449 - 720 13
B Inactive DFGin BLAminus in-in in-out 215 Type1 449 - 720 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       452        462        472        482 
gsdssdDWEI PDGQITVGQR IGSGSFGTVY KGKWHGDVAV 
       492        502        512        522 
KMLNVTAPTP QQLQAFKNEV GVLRKTRHVN ILLFMGYSTK 
       532        542        552        562 
PQLAIVTQWC EGSSLYHHLH IIETKFEMIK LIDIARQTAQ 
       572        582        592        602 
GMDYLHAKSI IHRDLKSNNI FLHEDLTVKI GDFGLATVks 
       612        622        632        642 
rwsgshqfeq lSGSILWMAP EVIRMQDKNP YSFQSDVYAF 
       652        662        672        682 
GIVLYELMTG QLPYSNINNR DQIIFMVGRG YLSPDLSKVR 
       692        702        712        722 
SNCPKAMKRL MAECLKKKRD ERPLFPQILA SIELLARSlp 

k
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None