Protein kinases in complex with TZ0 (Futibatinib)

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAplus 3 6MZWA
DFGin None 1 6MZWB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZQA 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZQB 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZWA 2.2 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZWB 2.2 Inactive DFGin None in-in none-none TZ0 Type1.5_Back

Protein kinases in complex with TZ0

Total number of genes: 2
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAplus 3 6MZWA
DFGin None 1 6MZWB
DFGout None 1 7D5OB
None None 1 7D5OA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OB 2.69 Inactive DFGout None out-out none-out TZ0 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OA 2.69 Inactive None None out-out none-out TZ0 Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZQA 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZQB 2.0 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZWA 2.2 Inactive DFGin BLAplus in-in none-none TZ0 Type1.5_Back
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 6MZWB 2.2 Inactive DFGin None in-in none-none TZ0 Type1.5_Back

Protein kinases in complex with TZ0

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGout None 1 7D5OB
None None 1 7D5OA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OB 2.69 Inactive DFGout None out-out none-out TZ0 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 7D5OA 2.69 Inactive None None out-out none-out TZ0 Type1