Ligand

Protein kinases in complex with T7I

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	None	4	8B8UA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8B8UA	1.5	Inactive	DFGin	None	in-none	out-out	T7I	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8B8UB	1.5	Inactive	DFGin	None	in-none	out-out	T7I	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8C0AA	1.7	Inactive	DFGin	None	in-none	out-out	T7I	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8C0AB	1.7	Inactive	DFGin	None	in-none	out-out	T7I	Type1

Protein kinases in complex with T7I

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	None	4	8B8UA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8B8UA	1.5	Inactive	DFGin	None	in-none	out-out	T7I	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8B8UB	1.5	Inactive	DFGin	None	in-none	out-out	T7I	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8C0AA	1.7	Inactive	DFGin	None	in-none	out-out	T7I	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	8C0AB	1.7	Inactive	DFGin	None	in-none	out-out	T7I	Type1

Protein kinases in complex with T7I

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type