Protein kinases in complex with RQ5

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUTE
DFGin ABAminus 2 8BUTB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTB 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTH 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTE 3.25 Active DFGin BLAminus in-in in-in RQ5 Type1

Protein kinases in complex with RQ5

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUTE
DFGin ABAminus 2 8BUTB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTB 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTH 3.25 Inactive DFGin ABAminus in-in in-in RQ5 Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUTE 3.25 Active DFGin BLAminus in-in in-in RQ5 Type1

Protein kinases in complex with RQ5

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type