Protein kinases in complex with RMF

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8P81A
DFGin ABAminus 2 8BU5B
DFGin None 1 8BU5E
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5B 3.134 Inactive DFGin ABAminus in-out in-in RMF Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5H 3.134 Inactive DFGin ABAminus in-in in-in RMF Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8P81A 2.68 Active DFGin BLAminus in-in in-in RMF Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5E 3.134 Inactive DFGin None in-out in-in RMF Type1

Protein kinases in complex with RMF

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8P81A
DFGin ABAminus 2 8BU5B
DFGin None 1 8BU5E
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5B 3.134 Inactive DFGin ABAminus in-out in-in RMF Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5H 3.134 Inactive DFGin ABAminus in-in in-in RMF Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8P81A 2.68 Active DFGin BLAminus in-in in-in RMF Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BU5E 3.134 Inactive DFGin None in-out in-in RMF Type1

Protein kinases in complex with RMF

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type