Protein kinases in complex with RKO

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUCE
DFGin ABAminus 1 8BUCB
DFGin None 1 8BUCH
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCB 3.85 Inactive DFGin ABAminus in-in in-in RKO Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCE 3.85 Active DFGin BLAminus in-in in-in RKO Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCH 3.85 Inactive DFGin None in-in in-in RKO Type1

Protein kinases in complex with RKO

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUCE
DFGin ABAminus 1 8BUCB
DFGin None 1 8BUCH
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCB 3.85 Inactive DFGin ABAminus in-in in-in RKO Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCE 3.85 Active DFGin BLAminus in-in in-in RKO Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUCH 3.85 Inactive DFGin None in-in in-in RKO Type1

Protein kinases in complex with RKO

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type