Protein kinases in complex with AXI (Axitinib)

Total number of genes: 2
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 2 4TWPB
DFGout BBAminus 2 4AG8A
DFGout None 1 4WA9B
None None 1 4WA9A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4TWPA 2.4 Active DFGin BLAminus in-in in-in AXI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4TWPB 2.4 Active DFGin BLAminus in-in in-in AXI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9B 2.2 Inactive DFGout None in-in out-in AXI Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9A 2.2 Inactive None None none-none out-in AXI Type1
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4AG8A 1.95 Inactive DFGout BBAminus in-in out-in AXI Type1
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4AGCA 2.0 Inactive DFGout BBAminus in-in out-in AXI Type1.5_Back

Protein kinases in complex with AXI

Total number of genes: 2
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 2 4TWPB
DFGout BBAminus 2 4AG8A
DFGout None 1 4WA9B
None None 1 4WA9A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4TWPA 2.4 Active DFGin BLAminus in-in in-in AXI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4TWPB 2.4 Active DFGin BLAminus in-in in-in AXI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9B 2.2 Inactive DFGout None in-in out-in AXI Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4WA9A 2.2 Inactive None None none-none out-in AXI Type1
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4AG8A 1.95 Inactive DFGout BBAminus in-in out-in AXI Type1
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4AGCA 2.0 Inactive DFGout BBAminus in-in out-in AXI Type1.5_Back

Protein kinases in complex with AXI

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type