PDB: 9UUR — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UURB

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK3 MK03_HUMAN 9UURB 3.36 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 26 - 374 0 None None Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UURA 3.36 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 379 0 SEP218,SEP222 None Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UUR — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UURB

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK3 MK03_HUMAN 9UURB 3.36 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out nonTYR APEdihe_aaioo APEdist_oooo ANP ATPlike 26 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9UURA 3.36 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 379 0 SEP218,SEP222 None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens

PDB: 9UUR — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism