PDB: 9TYI — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYIB
DFGin None 1 50.0% 9TYIA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYIB P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.825 16.147 BLAminus DFGAsp-rot-out -158.1954, -179.5955 59.6225, 60.4217 288.9167, -11.5795 -87.3908, 19.8656 285.0857, 60.4719 -61.4046, -37.4851 in-in in 9.831 Saltbr-in 3.08 HRD-in -74.3333, -41.922 47.9505, 23.96 in-in-out SNCiio in-out ActLoopNT-in 3.008 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -49.8366, 139.3201 APE9-dihe-na -176.3572, 175.4324 APE8-dihe-in -70.6794, 96.7671 APE8-rot-in 304.5863 APE67-dihe-in -90.8138, -0.2962 -92.0339, 28.3994 APE12-dist-in 10.198 APE11-dist-in 10.066 APE10-dist-out 13.341 APE9-dist-out 9.715 T185V None None EM 3.6 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyi CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYIA Q02750 441 386 393.0 No_ligand No_ligand Inactive DFGin 4.643 11.643 None DFGAsp-rot-in -162.2487, 166.5824 59.2745, 65.7793 174.7674, 8.0396 -45.3402, -64.1947 323.9519, 83.2889 81.3494, -74.2258 in-out in 8.299 Saltbr-out 3.791 HRD-in -61.848, -33.7956 74.6992, -13.6997 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.4325 APE8-rot-out 71.8497 APE67-dihe-in -96.1646, 7.5907 -65.3951, -42.8108 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S218D,S222D None None EM 3.6 999.0 999.0 A 405 252 67 0 0 13 [[68, 361]] 1.0 9tyi STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYI — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYIB
DFGin None 1 50.0% 9TYIA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYIB P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.825 16.147 BLAminus DFGAsp-rot-out -158.1954, -179.5955 59.6225, 60.4217 288.9167, -11.5795 -87.3908, 19.8656 285.0857, 60.4719 -61.4046, -37.4851 in-in in 9.831 Saltbr-in 3.08 HRD-in -74.3333, -41.922 47.9505, 23.96 in-in-out SNCiio in-out ActLoopNT-in 3.008 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -49.8366, 139.3201 APE9-dihe-na -176.3572, 175.4324 APE8-dihe-in -70.6794, 96.7671 APE8-rot-in 304.5863 APE67-dihe-in -90.8138, -0.2962 -92.0339, 28.3994 APE12-dist-in 10.198 APE11-dist-in 10.066 APE10-dist-out 13.341 APE9-dist-out 9.715 T185V None None EM 3.6 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyi Homo sapiens CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYIA Q02750 441 386 393.0 No_ligand No_ligand Inactive DFGin 4.643 11.643 None DFGAsp-rot-in -162.2487, 166.5824 59.2745, 65.7793 174.7674, 8.0396 -45.3402, -64.1947 323.9519, 83.2889 81.3494, -74.2258 in-out in 8.299 Saltbr-out 3.791 HRD-in -61.848, -33.7956 74.6992, -13.6997 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.4325 APE8-rot-out 71.8497 APE67-dihe-in -96.1646, 7.5907 -65.3951, -42.8108 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S218D,S222D None None EM 3.6 999.0 999.0 A 405 252 67 0 0 13 [[68, 361]] 1.0 9tyi Homo sapiens STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYI — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name