PDB: 9TYI — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYIB
DFGin None 1 50.0% 9TYIA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 9TYIB 3.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 11 - 360 0 None T185V Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYIA 3.6 Inactive DFGin‑None DFGAsp-rot-in in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 441 - 386 0 None S218D,S222D Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYI — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9TYIB
DFGin None 1 50.0% 9TYIA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 9TYIB 3.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 11 - 360 0 None T185V Mitogen-activated protein kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9TYIA 3.6 Inactive DFGin‑None DFGAsp-rot-in in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 441 - 386 0 None S218D,S222D Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens

PDB: 9TYI — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism