PDB: 9TYH — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 9TYHB
DFGin None 1 50.0% 9TYHA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYHB P28482 11 360 360.0 ADP:60401 ATPlike Inactive DFGin 5.459 15.19 BLAplus DFGAsp-rot-in -158.3023, 174.3807 58.1365, 58.2973 183.4571, 15.8768 -125.425, 47.0048 35.9435, 96.2059 -65.4254, -13.3824 in-out in 9.917 Saltbr-out 3.743 HRD-in -60.2511, -46.7126 48.1714, 22.5714 out-in-out SNCoio in-out ActLoopNT-in 3.048 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -47.9304, 124.5914 APE9-dihe-na -154.7683, 164.9647 APE8-dihe-in -100.2881, 145.849 APE8-rot-out 188.5709 APE67-dihe-out -75.6044, -28.697 -149.246, 121.4637 APE12-dist-out 14.17 APE11-dist-out 17.49 APE10-dist-out 18.954 APE9-dist-out 14.176 T185V None None EM 3.4 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyh CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYHA Q02750 441 382 393.0 ADP:60501 ATPlike Inactive DFGin 6.102 14.816 None DFGAsp-rot-out -91.7528, 174.0997 -73.7204, -176.4165 89.21, 5.6068 -105.6286, 32.3623 330.8177, 120.3359 60.0619, -141.2382 out-out out 13.325 Saltbr-out 13.29 HRD-out -89.1173, 95.6155 -77.9159, 5.803 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -145.4697, 145.3803 999.0, -46.5788 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S218D,S222D None None EM 3.4 999.0 999.0 A 405 263 58 0 0 14 [[68, 361]] 1.0 9tyh STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYH — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 9TYHB
DFGin None 1 50.0% 9TYHA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 9TYHB P28482 11 360 360.0 ADP:60401 ATPlike Inactive DFGin 5.459 15.19 BLAplus DFGAsp-rot-in -158.3023, 174.3807 58.1365, 58.2973 183.4571, 15.8768 -125.425, 47.0048 35.9435, 96.2059 -65.4254, -13.3824 in-out in 9.917 Saltbr-out 3.743 HRD-in -60.2511, -46.7126 48.1714, 22.5714 out-in-out SNCoio in-out ActLoopNT-in 3.048 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -47.9304, 124.5914 APE9-dihe-na -154.7683, 164.9647 APE8-dihe-in -100.2881, 145.849 APE8-rot-out 188.5709 APE67-dihe-out -75.6044, -28.697 -149.246, 121.4637 APE12-dist-out 14.17 APE11-dist-out 17.49 APE10-dist-out 18.954 APE9-dist-out 14.176 T185V None None EM 3.4 999.0 999.0 B 363 350 0 0 0 0 [[25, 313]] 1.0 9tyh Homo sapiens CMGC_MAPK1_HUMAN CMGC 5.3e-85 291.3 1 301 301 166 167 168 170 172 54 71 75 146 148 147 149 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
STE MAP2K1 MP2K1_HUMAN 9TYHA Q02750 441 382 393.0 ADP:60501 ATPlike Inactive DFGin 6.102 14.816 None DFGAsp-rot-out -91.7528, 174.0997 -73.7204, -176.4165 89.21, 5.6068 -105.6286, 32.3623 330.8177, 120.3359 60.0619, -141.2382 out-out out 13.325 Saltbr-out 13.29 HRD-out -89.1173, 95.6155 -77.9159, 5.803 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -145.4697, 145.3803 999.0, -46.5788 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S218D,S222D None None EM 3.4 999.0 999.0 A 405 263 58 0 0 14 [[68, 361]] 1.0 9tyh Homo sapiens STE_MAP2K1_HUMAN STE 7.9e-97 329.8 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9TYH — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name