PDB: 9MMR — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMRB Q02750 62 380 393.0 AGS:60701,LCJ:60703 ATPlike,Type3 Inactive DFGin 6.847 13.5448 BLBplus -144.47, 166.22 62.86, 45.64 -102.79, 155.22 38.56, 95.23 -78.03, 72.6 out-out out 15.3255 Saltbr-out 15.7338 HRD-in -59.38, -50.94 68.52, -2.49 out-out-out SNCooo out-out ActLoopNT-out 8.9519 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -61.82, 155.36 APE9-dihe-na -107.83, -179.82 APE8-dihe-out -105.89, -53.41 APE8-rot-in 308.85 APE67-dihe-out -136.82, 148.35 -127.86, 156.49 APE12-dist-out 17.0348 APE11-dist-out 22.0064 APE10-dist-out 24.0306 APE9-dist-out 13.5803 S218A,S222A None None EM 3.9 999.0 999.0 B 415.0 279.0 40 26 26 0 [[68, 361]] 1.0 9mmr STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMRA P04049 343 625 648.0 AGS:60701 ATPlike Inactive DFGin 5.4464 13.6261 BLBplus -135.09, 172.16 58.87, 36.16 -92.53, 159.81 52.16, 102.21 63.65, -134.37 out-out out 13.8632 Saltbr-out 12.3622 HRD-out -74.45, 80.03 -68.85, 163.44 out-out-out SNCooo out-out ActLoopNT-out 8.7183 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -153.07, 160.07 APE9-dihe-na 91.95, -174.93 APE8-dihe-in -63.61, 140.51 APE8-rot-in 299.95 APE67-dihe-in -59.35, -38.77 -86.72, -25.37 APE12-dist-out 15.0543 APE11-dist-out 14.7515 APE10-dist-out 11.0339 APE9-dist-out 8.4046 Q156R,Y340D,Y341D,D587E SEP621 SEP621 EM 3.9 999.0 999.0 A 681.0 283.0 0 30 30 0 [[349, 608]] 1.0 9mmr TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMR — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMRB Q02750 62 380 393.0 AGS:60701,LCJ:60703 ATPlike,Type3 Inactive DFGin 6.847 13.5448 BLBplus -144.47, 166.22 62.86, 45.64 -102.79, 155.22 38.56, 95.23 -78.03, 72.6 out-out out 15.3255 Saltbr-out 15.7338 HRD-in -59.38, -50.94 68.52, -2.49 out-out-out SNCooo out-out ActLoopNT-out 8.9519 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -61.82, 155.36 APE9-dihe-na -107.83, -179.82 APE8-dihe-out -105.89, -53.41 APE8-rot-in 308.85 APE67-dihe-out -136.82, 148.35 -127.86, 156.49 APE12-dist-out 17.0348 APE11-dist-out 22.0064 APE10-dist-out 24.0306 APE9-dist-out 13.5803 S218A,S222A None None EM 3.9 999.0 999.0 B 415.0 279.0 40 26 26 0 [[68, 361]] 1.0 9mmr Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMRA P04049 343 625 648.0 AGS:60701 ATPlike Inactive DFGin 5.4464 13.6261 BLBplus -135.09, 172.16 58.87, 36.16 -92.53, 159.81 52.16, 102.21 63.65, -134.37 out-out out 13.8632 Saltbr-out 12.3622 HRD-out -74.45, 80.03 -68.85, 163.44 out-out-out SNCooo out-out ActLoopNT-out 8.7183 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -153.07, 160.07 APE9-dihe-na 91.95, -174.93 APE8-dihe-in -63.61, 140.51 APE8-rot-in 299.95 APE67-dihe-in -59.35, -38.77 -86.72, -25.37 APE12-dist-out 15.0543 APE11-dist-out 14.7515 APE10-dist-out 11.0339 APE9-dist-out 8.4046 Q156R,Y340D,Y341D,D587E SEP621 SEP621 EM 3.9 999.0 999.0 A 681.0 283.0 0 30 30 0 [[349, 608]] 1.0 9mmr Homo sapiens TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMR — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name