PDB: 9MMQ — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMQB Q02750 62 380 393.0 AGS:701,LCJ:703 ATPlike,Type3 Inactive DFGin 6.6749 13.4889 BLBplus -138.6, 170.41 60.57, 44.79 -97.28, 158.99 35.24, 93.11 -75.64, 83.14 out-out out 15.4214 Saltbr-out 15.6346 HRD-in -61.2, -52.92 69.79, -9.3 out-out-out SNCooo out-out ActLoopNT-out 9.0103 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -65.78, 148.58 APE9-dihe-na -99.52, -176.8 APE8-dihe-out -104.42, -44.51 APE8-rot-in 299.56 APE67-dihe-out -150.89, 153.99 -135.56, 174.2 APE12-dist-out 17.2664 APE11-dist-out 22.0929 APE10-dist-out 24.0771 APE9-dist-out 13.54 S218A,S222A None None EM 2.9 999.0 999.0 B 415.0 279.0 40 26 26 0 [[68, 361]] 1.0 9mmq STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMQA P04049 341 612 648.0 AGS:701 ATPlike Inactive DFGin 6.0418 13.4878 BLBplus -128.47, 173.58 60.41, 41.33 -95.4, 154.76 40.5, 88.25 68.22, -137.22 out-out out 13.7306 Saltbr-out 12.7147 HRD-out -73.84, 78.36 -65.55, 163.21 out-out-out SNCooo out-out ActLoopNT-out 9.1331 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -154.13, 160.3 APE9-dihe-na 98.38, -176.64 APE8-dihe-in -67.06, 138.58 APE8-rot-in 288.86 APE67-dihe-in -64.64, -31.65 -87.38, -18.69 APE12-dist-out 15.1677 APE11-dist-out 14.4229 APE10-dist-out 10.8266 APE9-dist-out 8.1068 Q156R,D587E None None EM 2.9 999.0 999.0 A 681.0 272.0 0 30 30 0 [[349, 608]] 1.0 9mmq TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMQ — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9MMQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9MMQB Q02750 62 380 393.0 AGS:701,LCJ:703 ATPlike,Type3 Inactive DFGin 6.6749 13.4889 BLBplus -138.6, 170.41 60.57, 44.79 -97.28, 158.99 35.24, 93.11 -75.64, 83.14 out-out out 15.4214 Saltbr-out 15.6346 HRD-in -61.2, -52.92 69.79, -9.3 out-out-out SNCooo out-out ActLoopNT-out 9.0103 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -65.78, 148.58 APE9-dihe-na -99.52, -176.8 APE8-dihe-out -104.42, -44.51 APE8-rot-in 299.56 APE67-dihe-out -150.89, 153.99 -135.56, 174.2 APE12-dist-out 17.2664 APE11-dist-out 22.0929 APE10-dist-out 24.0771 APE9-dist-out 13.54 S218A,S222A None None EM 2.9 999.0 999.0 B 415.0 279.0 40 26 26 0 [[68, 361]] 1.0 9mmq Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9MMQA P04049 341 612 648.0 AGS:701 ATPlike Inactive DFGin 6.0418 13.4878 BLBplus -128.47, 173.58 60.41, 41.33 -95.4, 154.76 40.5, 88.25 68.22, -137.22 out-out out 13.7306 Saltbr-out 12.7147 HRD-out -73.84, 78.36 -65.55, 163.21 out-out-out SNCooo out-out ActLoopNT-out 9.1331 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -154.13, 160.3 APE9-dihe-na 98.38, -176.64 APE8-dihe-in -67.06, 138.58 APE8-rot-in 288.86 APE67-dihe-in -64.64, -31.65 -87.38, -18.69 APE12-dist-out 15.1677 APE11-dist-out 14.4229 APE10-dist-out 10.8266 APE9-dist-out 8.1068 Q156R,D587E None None EM 2.9 999.0 999.0 A 681.0 272.0 0 30 30 0 [[349, 608]] 1.0 9mmq Homo sapiens TKL_RAF1_HUMAN TKL 2e-80 276.3 3.0 266.0 264.0 485 486 487 489 491 375 393 397 465 467 466 468.0 530 515 510 509 508 507 506 505 504 422 RAF proto-oncogene serine/threonine-protein kinase

PDB: 9MMQ — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name