| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Active | DFGin | BLAminus | in-in | in-in | PE3 PE3 YPK | Allosteric Allosteric Type1 | 8 - 312 | 9 |
| B | Inactive | DFGin | None | in-in | in-in | PE3 PE3 YPK | Allosteric Allosteric Type1 | 9 - 312 | 9 |
Representative sequence - Chain B
- - 5 15
msyyhhhhhh dydipttenl yfqgsmaldv ksrAKRYEKL
25 35 45 55
DFLGEGQFAT VYKARDKNTN QIVAIKKIKL GHRseakdGI
65 75 85 95
NRTALREIKL LQELSHPNII GLLDAFGHKS NISLVFDFME
105 115 125 135
TDLEVIIKDN SLVLTPSHIK AYMLMTLQGL EYLHQHRILH
145 155 165 175
RDLKPNNLLL DENGVLKLAD FGLAKSFgdp nrayehQVVT
185 195 205 215
RWYRAPELLF GARMYGVGVD MWAVGCILAE LLLRVPFLPG
225 235 245 255
DSDLDQLTRI FETLGTPTEE QWPDMCSLPD YVTFKSFPGI
265 275 285 295
PLHHIFSAAG DDLLDLIQGL FLFNPCARIT ATQALKMKYF
305 315 325 335
SNRPGPTPGC QLPRPNCpve tlkeqsnpal aikrkrteal
345
eqgglpkkli f