Ligand: PE3

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8R9SA
DFGin None 1 50.0% 8R9SB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK7 CDK7_HUMAN 8R9SA 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_niii PE3, PE3, YPK Allosteric, Allosteric, Type1 8 - 312 0 None W132R,S164D,T170E Cyclin-dependent kinase 7
CMGC CDK7 CDK7_HUMAN 8R9SB 2.78 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioo APEdist_niii PE3, PE3, YPK Allosteric, Allosteric, Type1 9 - 312 0 None W132R,S164D,T170E Cyclin-dependent kinase 7

Ligand: PE3

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8R9SA
DFGin None 1 50.0% 8R9SB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK7 CDK7_HUMAN 8R9SA 2.78 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_niii PE3, PE3, YPK Allosteric, Allosteric, Type1 8 - 312 0 None W132R,S164D,T170E Cyclin-dependent kinase 7 Homo sapiens
CMGC CDK7 CDK7_HUMAN 8R9SB 2.78 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioo APEdist_niii PE3, PE3, YPK Allosteric, Allosteric, Type1 9 - 312 0 None W132R,S164D,T170E Cyclin-dependent kinase 7 Homo sapiens

Ligand: PE3

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism