| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR4 | FGFR4_HUMAN | 8KH9A | P22455 | 454 | 752 | 802.0 | VVW:903 | Type1 | Inactive | DFGin | 5.6284 | 13.2287 | BLBplus | -116.73, 162.01 | 54.49, 42.82 | -90.48, 158.22 | 47.04, 88.15 | 53.89, 22.89 | in-in | in | 7.5394 | Saltbr-in | 2.6915 | HRD-in | -76.16, -55.94 | 82.55, -10.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.7222 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -79.55, 140.78 | APE9-dihe-in | -111.22, 92.1 | APE8-dihe-out | -57.69, -22.37 | APE8-rot-na | 333.28 | APE67-dihe-in | -71.01, -5.51 | -56.46, -26.43 | APE12-dist-na | 20.3132 | APE11-dist-na | 21.8343 | APE10-dist-na | 17.5883 | APE9-dist-out | 11.963 | C477A,V550M,R664E | None | None | XRAY | 1.42 | 0.171 | 0.193 | A | 300.0 | 299.0 | 0 | 30 | 30 | 0 | [[467, 745]] | 1.0 | 8kh9 | TYR_FGFR4_HUMAN | TYR | 6.3e-101 | 343.0 | 1.0 | 261.0 | 261.0 | 629 | 630 | 631 | 633 | 635 | 503 | 520 | 524 | 609 | 611 | 610 | 612.0 | 671 | 659 | 654 | 653 | 652 | 651 | 650 | 649 | 648 | 551 | Fibroblast growth factor receptor 4 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR4 | FGFR4_HUMAN | 8KH9A | P22455 | 454 | 752 | 802.0 | VVW:903 | Type1 | Inactive | DFGin | 5.6284 | 13.2287 | BLBplus | -116.73, 162.01 | 54.49, 42.82 | -90.48, 158.22 | 47.04, 88.15 | 53.89, 22.89 | in-in | in | 7.5394 | Saltbr-in | 2.6915 | HRD-in | -76.16, -55.94 | 82.55, -10.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.7222 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -79.55, 140.78 | APE9-dihe-in | -111.22, 92.1 | APE8-dihe-out | -57.69, -22.37 | APE8-rot-na | 333.28 | APE67-dihe-in | -71.01, -5.51 | -56.46, -26.43 | APE12-dist-na | 20.3132 | APE11-dist-na | 21.8343 | APE10-dist-na | 17.5883 | APE9-dist-out | 11.963 | C477A,V550M,R664E | None | None | XRAY | 1.42 | 0.171 | 0.193 | A | 300.0 | 299.0 | 0 | 30 | 30 | 0 | [[467, 745]] | 1.0 | 8kh9 | Homo sapiens | TYR_FGFR4_HUMAN | TYR | 6.3e-101 | 343.0 | 1.0 | 261.0 | 261.0 | 629 | 630 | 631 | 633 | 635 | 503 | 520 | 524 | 609 | 611 | 610 | 612.0 | 671 | 659 | 654 | 653 | 652 | 651 | 650 | 649 | 648 | 551 | Fibroblast growth factor receptor 4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|