PDB: 8GW3 — TKL M3K7_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 3 75.0% 8GW3B
DFGin None 1 25.0% 8GW3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K7 M3K7_HUMAN 8GW3A O43318 27 497 606.0 No_ligand No_ligand Inactive DFGin 6.6472 11.7225 None -119.33, 8.38 -158.05, 154.61 -116.24, 147.16 288.24, 68.47 -75.8, 166.21 out-out out 13.9572 Saltbr-out 9.2042 HRD-in -71.65, -49.3 87.44, -14.15 out-out-out SNCooo out-out ActLoopNT-out 10.0952 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -82.82, -0.21 APE9-dihe-na 77.02, 24.75 APE8-dihe-out -104.16, 8.77 APE8-rot-in 301.46 APE67-dihe-in -66.78, -13.89 -61.71, -40.48 APE12-dist-in 12.1847 APE11-dist-out 14.8778 APE10-dist-out 9.0724 APE9-dist-out 10.7885 None None None XRAY 2.05 0.223 0.258 A 326.0 277.0 0 25 25 0 [[36, 286]] 1.0 8gw3 TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3B O43318 27 497 606.0 No_ligand No_ligand Inactive DFGinter 7.3073 10.8739 None -117.09, 7.66 -155.39, 153.46 -120.54, 145.11 298.27, 66.91 -71.46, 166.75 out-out out 13.5798 Saltbr-out 9.5828 HRD-in -69.79, -54.63 87.1, -10.39 out-out-out SNCooo out-out ActLoopNT-out 9.8721 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -79.79, -8.62 APE9-dihe-na 73.87, 28.3 APE8-dihe-out -98.45, 5.64 APE8-rot-in 294.07 APE67-dihe-in -64.55, -14.4 -62.64, -34.37 APE12-dist-in 11.4121 APE11-dist-out 15.7259 APE10-dist-out 10.0313 APE9-dist-out 10.9687 None None None XRAY 2.05 0.223 0.258 B 326.0 277.0 0 25 25 0 [[36, 286]] 1.0 8gw3 TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3C O43318 25 497 606.0 No_ligand No_ligand Inactive DFGinter 7.0005 10.8383 None -118.88, 9.98 -158.01, 154.4 -119.85, 146.31 299.32, 82.07 -75.37, 164.49 out-none out 13.1301 Saltbr-none 999.0 HRD-in -72.49, -54.99 85.65, -8.16 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -79.4, -8.44 APE9-dihe-na 70.7, 25.06 APE8-dihe-out -96.14, 11.17 APE8-rot-in 290.65 APE67-dihe-in -65.82, -14.66 -63.16, -38.68 APE12-dist-in 9.5745 APE11-dist-out 14.5048 APE10-dist-out 9.4631 APE9-dist-out 10.6786 None None None XRAY 2.05 0.223 0.258 C 326.0 276.0 3 25 22 3 [[36, 286]] 1.0 8gw3 TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3D O43318 27 495 606.0 No_ligand No_ligand Inactive DFGinter 7.4472 10.844 None -119.27, 7.31 -156.44, 153.6 -121.29, 145.39 298.84, 83.74 -68.76, 164.64 out-out out 12.8254 Saltbr-out 10.0369 HRD-in -70.85, -56.03 85.08, -6.45 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na 89.94, -46.56 APE9-dihe-na 70.84, 30.69 APE8-dihe-out -97.92, 9.04 APE8-rot-in 302.34 APE67-dihe-in -65.06, -14.35 -59.83, -33.2 APE12-dist-in 12.4348 APE11-dist-in 12.7132 APE10-dist-out 9.8552 APE9-dist-out 10.5691 None None None XRAY 2.05 0.223 0.258 D 326.0 274.0 3 25 22 3 [[36, 286]] 1.0 8gw3 TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7

PDB: 8GW3 — TKL M3K7_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 3 75.0% 8GW3B
DFGin None 1 25.0% 8GW3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K7 M3K7_HUMAN 8GW3A O43318 27 497 606.0 No_ligand No_ligand Inactive DFGin 6.6472 11.7225 None -119.33, 8.38 -158.05, 154.61 -116.24, 147.16 288.24, 68.47 -75.8, 166.21 out-out out 13.9572 Saltbr-out 9.2042 HRD-in -71.65, -49.3 87.44, -14.15 out-out-out SNCooo out-out ActLoopNT-out 10.0952 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -82.82, -0.21 APE9-dihe-na 77.02, 24.75 APE8-dihe-out -104.16, 8.77 APE8-rot-in 301.46 APE67-dihe-in -66.78, -13.89 -61.71, -40.48 APE12-dist-in 12.1847 APE11-dist-out 14.8778 APE10-dist-out 9.0724 APE9-dist-out 10.7885 None None None XRAY 2.05 0.223 0.258 A 326.0 277.0 0 25 25 0 [[36, 286]] 1.0 8gw3 Homo sapiens TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3B O43318 27 497 606.0 No_ligand No_ligand Inactive DFGinter 7.3073 10.8739 None -117.09, 7.66 -155.39, 153.46 -120.54, 145.11 298.27, 66.91 -71.46, 166.75 out-out out 13.5798 Saltbr-out 9.5828 HRD-in -69.79, -54.63 87.1, -10.39 out-out-out SNCooo out-out ActLoopNT-out 9.8721 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -79.79, -8.62 APE9-dihe-na 73.87, 28.3 APE8-dihe-out -98.45, 5.64 APE8-rot-in 294.07 APE67-dihe-in -64.55, -14.4 -62.64, -34.37 APE12-dist-in 11.4121 APE11-dist-out 15.7259 APE10-dist-out 10.0313 APE9-dist-out 10.9687 None None None XRAY 2.05 0.223 0.258 B 326.0 277.0 0 25 25 0 [[36, 286]] 1.0 8gw3 Homo sapiens TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3C O43318 25 497 606.0 No_ligand No_ligand Inactive DFGinter 7.0005 10.8383 None -118.88, 9.98 -158.01, 154.4 -119.85, 146.31 299.32, 82.07 -75.37, 164.49 out-none out 13.1301 Saltbr-none 999.0 HRD-in -72.49, -54.99 85.65, -8.16 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -79.4, -8.44 APE9-dihe-na 70.7, 25.06 APE8-dihe-out -96.14, 11.17 APE8-rot-in 290.65 APE67-dihe-in -65.82, -14.66 -63.16, -38.68 APE12-dist-in 9.5745 APE11-dist-out 14.5048 APE10-dist-out 9.4631 APE9-dist-out 10.6786 None None None XRAY 2.05 0.223 0.258 C 326.0 276.0 3 25 22 3 [[36, 286]] 1.0 8gw3 Homo sapiens TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 8GW3D O43318 27 495 606.0 No_ligand No_ligand Inactive DFGinter 7.4472 10.844 None -119.27, 7.31 -156.44, 153.6 -121.29, 145.39 298.84, 83.74 -68.76, 164.64 out-out out 12.8254 Saltbr-out 10.0369 HRD-in -70.85, -56.03 85.08, -6.45 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na 89.94, -46.56 APE9-dihe-na 70.84, 30.69 APE8-dihe-out -97.92, 9.04 APE8-rot-in 302.34 APE67-dihe-in -65.06, -14.35 -59.83, -33.2 APE12-dist-in 12.4348 APE11-dist-in 12.7132 APE10-dist-out 9.8552 APE9-dist-out 10.5691 None None None XRAY 2.05 0.223 0.258 D 326.0 274.0 3 25 22 3 [[36, 286]] 1.0 8gw3 Homo sapiens TKL_MAP3K7_HUMAN TKL 4.6e-74 255.3 2.0 266.0 265.0 174 175 176 178 180 63 77 81 153 155 154 156.0 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7

PDB: 8GW3 — TKL M3K7_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name