6YG1

MAP2K7 (Dual specificity mitogen-activated protein kinase kinase 7)
Group: STE
Uniprot: MP2K7_HUMAN
Organism: Homo sapiens
Domain boundary: 120 - 380
Resolu: 2.22

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 86 - 404 0
B Active DFGin BLAminus in-in in-in No_ligand No_ligand 93 - 404 0
C Active DFGin BLAminus in-in in-in No_ligand No_ligand 86 - 405 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
        67         77         87         97 
smsspqhptp parprhmlgl pstlftprSM ESIEIDQKLQ 
       107        117        127        137 
EIMKQTGYLT IGGQRYQAEI NDLENLGEMG sgtcgQVWKM 
       147        157        167        177 
RFRKTGHVIA VKQMRRSGNK EENKRILMDL DVVLKSHDCP 
       187        197        207        217 
YIVQCFGTFI TNTDVFIAME LMGTCAEKLK KRMQGPIPER 
       227        237        247        257 
ILGKMTVAIV KALYYLKEKH GVIHRDVKPS NILLDERGQI 
       267        277        287        297 
KLCDFGISGR LVDDKAKDRS AGCAAYMAPE RIDPPDPTKP 
       307        317        327        337 
DYDIRADVWS LGISLVELAT GQFPYKNCKT DFEVLTKVLQ 
       347        357        367        377 
EEPPLLPGHM GFSGDFQSFV KDCLTKDHRK RPKYNKLLEH 
       387        397 
SFIKRYETLE VDVASWFKDV MAKTESPR
Lower-case residues are disordered in structure.
Mutations: S271D,T275D
Phosphorylation: None