PDB: 6YG1 — STE MP2K7_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6YG1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K7 MP2K7_HUMAN 6YG1A O14733 86 404 419.0 No_ligand No_ligand Active DFGin 5.9305 14.6445 BLAminus -139.75, -178.51 55.48, 92.06 -111.01, 29.63 315.16, 93.19 -69.74, -26.75 in-na in 8.1105 Saltbr-na 3.0077 HRD-in -72.55, -50.64 76.96, 6.43 na-in-in SNCaii in-in ActLoopNT-in 2.9082 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -79.26, 103.62 APE9-dihe-na 136.94, 169.34 APE8-dihe-in -92.63, 126.44 APE8-rot-na 170.6 APE67-dihe-in -62.5, -26.78 -51.81, -44.28 APE12-dist-in 12.7902 APE11-dist-in 9.924 APE10-dist-in 5.3977 APE9-dist-in 3.4564 S271D,T275D None None XRAY 2.22 0.205 0.232 A 348.0 314.0 5 27 27 0 [[120, 380]] 1.0 6yg1 STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG1B O14733 93 404 419.0 No_ligand No_ligand Active DFGin 5.8891 14.977 BLAminus -142.37, -179.59 56.42, 90.83 -110.86, 29.11 314.92, 97.64 -68.6, -26.26 in-na in 8.8917 Saltbr-na 4.9518 HRD-in -68.85, -52.56 75.41, 8.03 na-in-in SNCaii in-in ActLoopNT-in 2.9323 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -77.32, 102.16 APE9-dihe-na 141.15, 166.92 APE8-dihe-in -91.69, 124.38 APE8-rot-na 170.36 APE67-dihe-in -60.55, -28.59 -53.55, -45.43 APE12-dist-in 12.7222 APE11-dist-in 9.7884 APE10-dist-in 5.3121 APE9-dist-in 3.4756 S271D,T275D None None XRAY 2.22 0.205 0.232 B 348.0 307.0 5 27 27 0 [[120, 380]] 1.0 6yg1 STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG1C O14733 86 405 419.0 No_ligand No_ligand Active DFGin 5.867 14.8801 BLAminus -143.88, 179.51 55.81, 91.73 -110.17, 29.88 314.81, 97.84 -67.15, -27.41 in-na in 8.669 Saltbr-na 3.7601 HRD-in -70.3, -52.02 75.96, 8.08 na-in-in SNCaii in-in ActLoopNT-in 2.9308 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -78.45, 102.93 APE9-dihe-na 140.93, 165.22 APE8-dihe-in -88.99, 125.59 APE8-rot-na 170.38 APE67-dihe-in -58.75, -28.89 -54.03, -43.27 APE12-dist-in 12.6582 APE11-dist-in 9.8249 APE10-dist-in 5.3379 APE9-dist-in 3.4565 S271D,T275D None None XRAY 2.22 0.205 0.232 C 348.0 315.0 5 27 27 0 [[120, 380]] 1.0 6yg1 STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7

PDB: 6YG1 — STE MP2K7_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6YG1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K7 MP2K7_HUMAN 6YG1A O14733 86 404 419.0 No_ligand No_ligand Active DFGin 5.9305 14.6445 BLAminus -139.75, -178.51 55.48, 92.06 -111.01, 29.63 315.16, 93.19 -69.74, -26.75 in-na in 8.1105 Saltbr-na 3.0077 HRD-in -72.55, -50.64 76.96, 6.43 na-in-in SNCaii in-in ActLoopNT-in 2.9082 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -79.26, 103.62 APE9-dihe-na 136.94, 169.34 APE8-dihe-in -92.63, 126.44 APE8-rot-na 170.6 APE67-dihe-in -62.5, -26.78 -51.81, -44.28 APE12-dist-in 12.7902 APE11-dist-in 9.924 APE10-dist-in 5.3977 APE9-dist-in 3.4564 S271D,T275D None None XRAY 2.22 0.205 0.232 A 348.0 314.0 5 27 27 0 [[120, 380]] 1.0 6yg1 Homo sapiens STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG1B O14733 93 404 419.0 No_ligand No_ligand Active DFGin 5.8891 14.977 BLAminus -142.37, -179.59 56.42, 90.83 -110.86, 29.11 314.92, 97.64 -68.6, -26.26 in-na in 8.8917 Saltbr-na 4.9518 HRD-in -68.85, -52.56 75.41, 8.03 na-in-in SNCaii in-in ActLoopNT-in 2.9323 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -77.32, 102.16 APE9-dihe-na 141.15, 166.92 APE8-dihe-in -91.69, 124.38 APE8-rot-na 170.36 APE67-dihe-in -60.55, -28.59 -53.55, -45.43 APE12-dist-in 12.7222 APE11-dist-in 9.7884 APE10-dist-in 5.3121 APE9-dist-in 3.4756 S271D,T275D None None XRAY 2.22 0.205 0.232 B 348.0 307.0 5 27 27 0 [[120, 380]] 1.0 6yg1 Homo sapiens STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG1C O14733 86 405 419.0 No_ligand No_ligand Active DFGin 5.867 14.8801 BLAminus -143.88, 179.51 55.81, 91.73 -110.17, 29.88 314.81, 97.84 -67.15, -27.41 in-na in 8.669 Saltbr-na 3.7601 HRD-in -70.3, -52.02 75.96, 8.08 na-in-in SNCaii in-in ActLoopNT-in 2.9308 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -78.45, 102.93 APE9-dihe-na 140.93, 165.22 APE8-dihe-in -88.99, 125.59 APE8-rot-na 170.38 APE67-dihe-in -58.75, -28.89 -54.03, -43.27 APE12-dist-in 12.6582 APE11-dist-in 9.8249 APE10-dist-in 5.3379 APE9-dist-in 3.4565 S271D,T275D None None XRAY 2.22 0.205 0.232 C 348.0 315.0 5 27 27 0 [[120, 380]] 1.0 6yg1 Homo sapiens STE_MAP2K7_HUMAN STE 5.1e-80 274.6 2.0 257.0 256.0 260 261 262 264 266 149 166 170 240 242 241 243.0 304 287 282 281 280 279 278 277 276 197 Dual specificity mitogen-activated protein kinase kinase 7

PDB: 6YG1 — STE MP2K7_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name