PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CLK1 CLK1_HUMAN 5J1WA 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6FB Type1 148 - 483 0 None None Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6FB Type1 148 - 482 0 None None Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_oioo 6FB, 6FB Type1, Allosteric 148 - 483 0 None None Dual specificity protein kinase CLK1

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CLK1 CLK1_HUMAN 5J1WA 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6FB Type1 148 - 483 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 5J1WB 2.42 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6FB Type1 148 - 482 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 5J1WC 2.42 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_oioo 6FB, 6FB Type1, Allosteric 148 - 483 0 None None Dual specificity protein kinase CLK1 Homo sapiens

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism