PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1WA P49759 148 483 484.0 6FB:60506 Type1 Active DFGin 7.1724 14.3259 BLAminus -121.81, 173.7 71.87, 86.58 -105.02, 20.94 296.61, 84.3 -77.49, -14.22 in-in in 8.5488 Saltbr-in 2.5641 HRD-in -71.53, -50.92 81.49, -14.91 in-in-in SNCiii in-in ActLoopNT-in 2.9036 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.47, 167.51 APE9-dihe-na 77.02, 140.17 APE8-dihe-in -56.28, 137.97 APE8-rot-in 295.84 APE67-dihe-in -62.06, -22.4 -61.94, -35.28 APE12-dist-in 13.6052 APE11-dist-in 11.4365 APE10-dist-in 7.2516 APE9-dist-in 3.0421 None None None XRAY 2.42 0.191 0.228 A 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WB P49759 148 482 484.0 6FB:60503 Type1 Active DFGin 7.2901 14.2646 BLAminus -120.99, 173.46 72.42, 86.12 -105.34, 21.92 296.07, 87.01 -75.02, -15.34 in-in in 8.5851 Saltbr-in 2.5852 HRD-in -69.32, -50.91 80.3, -14.73 in-in-in SNCiii in-in ActLoopNT-in 2.8972 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.41, 167.18 APE9-dihe-na 77.9, 139.82 APE8-dihe-in -54.28, 138.17 APE8-rot-in 296.7 APE67-dihe-in -62.44, -21.37 -62.69, -34.82 APE12-dist-in 13.6477 APE11-dist-in 11.342 APE10-dist-in 7.196 APE9-dist-in 3.035 None None None XRAY 2.42 0.191 0.228 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WC P49759 148 483 484.0 6FB:60505,6FB:60506 Type1,Allosteric Inactive DFGin 7.1425 14.2862 BLAminus -122.18, 173.27 71.94, 86.76 -106.83, 22.04 296.04, 87.14 -77.19, -12.48 in-in in 8.5036 Saltbr-in 2.5683 HRD-in -74.28, -51.47 84.87, -18.08 in-in-out SNCiio in-out ActLoopNT-in 2.8804 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -128.25, 150.31 APE9-dihe-na -78.45, -169.37 APE8-dihe-in -56.02, 117.75 APE8-rot-in 301.81 APE67-dihe-out -74.26, -11.87 -128.54, 128.96 APE12-dist-out 14.7541 APE11-dist-in 12.3342 APE10-dist-out 9.2098 APE9-dist-out 8.676 None None None XRAY 2.42 0.191 0.228 C 339.0 314.0 22 25 25 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1WA P49759 148 483 484.0 6FB:60506 Type1 Active DFGin 7.1724 14.3259 BLAminus -121.81, 173.7 71.87, 86.58 -105.02, 20.94 296.61, 84.3 -77.49, -14.22 in-in in 8.5488 Saltbr-in 2.5641 HRD-in -71.53, -50.92 81.49, -14.91 in-in-in SNCiii in-in ActLoopNT-in 2.9036 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.47, 167.51 APE9-dihe-na 77.02, 140.17 APE8-dihe-in -56.28, 137.97 APE8-rot-in 295.84 APE67-dihe-in -62.06, -22.4 -61.94, -35.28 APE12-dist-in 13.6052 APE11-dist-in 11.4365 APE10-dist-in 7.2516 APE9-dist-in 3.0421 None None None XRAY 2.42 0.191 0.228 A 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WB P49759 148 482 484.0 6FB:60503 Type1 Active DFGin 7.2901 14.2646 BLAminus -120.99, 173.46 72.42, 86.12 -105.34, 21.92 296.07, 87.01 -75.02, -15.34 in-in in 8.5851 Saltbr-in 2.5852 HRD-in -69.32, -50.91 80.3, -14.73 in-in-in SNCiii in-in ActLoopNT-in 2.8972 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.41, 167.18 APE9-dihe-na 77.9, 139.82 APE8-dihe-in -54.28, 138.17 APE8-rot-in 296.7 APE67-dihe-in -62.44, -21.37 -62.69, -34.82 APE12-dist-in 13.6477 APE11-dist-in 11.342 APE10-dist-in 7.196 APE9-dist-in 3.035 None None None XRAY 2.42 0.191 0.228 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WC P49759 148 483 484.0 6FB:60505,6FB:60506 Type1,Allosteric Inactive DFGin 7.1425 14.2862 BLAminus -122.18, 173.27 71.94, 86.76 -106.83, 22.04 296.04, 87.14 -77.19, -12.48 in-in in 8.5036 Saltbr-in 2.5683 HRD-in -74.28, -51.47 84.87, -18.08 in-in-out SNCiio in-out ActLoopNT-in 2.8804 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -128.25, 150.31 APE9-dihe-na -78.45, -169.37 APE8-dihe-in -56.02, 117.75 APE8-rot-in 301.81 APE67-dihe-out -74.26, -11.87 -128.54, 128.96 APE12-dist-out 14.7541 APE11-dist-in 12.3342 APE10-dist-out 9.2098 APE9-dist-out 8.676 None None None XRAY 2.42 0.191 0.228 C 339.0 314.0 22 25 25 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name