PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4WD5A
DFGinter None 1 50.0% 4WD5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4WD5A P00533 694 1021 1210.0 3LH:1101 Type1 Inactive DFGin 5.4579 14.3267 BLAminus -163.55, -174.21 53.25, 61.87 -88.09, 5.1 292.2, 106.75 -57.38, -39.62 out-out out 10.1006 Saltbr-out 3.9089 HRD-out -88.47, 107.17 -64.41, -38.01 out-in-out SNCoio in-out ActLoopNT-in 3.2129 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.87, 132.32 APE9-dihe-in -145.35, 143.46 APE8-dihe-in -90.09, 123.82 APE8-rot-na 33.05 APE67-dihe-in -61.34, -40.63 -65.68, -40.65 APE12-dist-na 11.8521 APE11-dist-na 9.4557 APE10-dist-na 10.0376 APE9-dist-out 8.0729 T790M None None XRAY 3.3 0.211 0.239 A 331.0 307.0 0 30 30 0 [[712, 970]] 1.0 4wd5 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WD5B P00533 697 1016 1210.0 No_ligand No_ligand Inactive DFGinter 9.2476 4.4249 None -72.57, 139.36 -100.73, 10.04 -62.48, 143.44 260.7, 137.62 58.63, 39.1 in-out in 7.7295 Saltbr-out 3.7391 HRD-out -90.94, 114.01 -64.78, -40.5 out-out-out SNCooo out-out ActLoopNT-out 4.9778 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -60.44, 137.91 APE9-dihe-in -137.14, 159.08 APE8-dihe-in -84.32, 85.1 APE8-rot-na 36.97 APE67-dihe-in -61.6, -40.36 -63.96, -40.18 APE12-dist-na 16.5849 APE11-dist-na 15.8297 APE10-dist-na 16.9449 APE9-dist-out 8.8365 T790M None None XRAY 3.3 0.211 0.239 B 331.0 304.0 5 30 25 5 [[712, 970]] 1.0 4wd5 TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4WD5A
DFGinter None 1 50.0% 4WD5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4WD5A P00533 694 1021 1210.0 3LH:1101 Type1 Inactive DFGin 5.4579 14.3267 BLAminus -163.55, -174.21 53.25, 61.87 -88.09, 5.1 292.2, 106.75 -57.38, -39.62 out-out out 10.1006 Saltbr-out 3.9089 HRD-out -88.47, 107.17 -64.41, -38.01 out-in-out SNCoio in-out ActLoopNT-in 3.2129 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.87, 132.32 APE9-dihe-in -145.35, 143.46 APE8-dihe-in -90.09, 123.82 APE8-rot-na 33.05 APE67-dihe-in -61.34, -40.63 -65.68, -40.65 APE12-dist-na 11.8521 APE11-dist-na 9.4557 APE10-dist-na 10.0376 APE9-dist-out 8.0729 T790M None None XRAY 3.3 0.211 0.239 A 331.0 307.0 0 30 30 0 [[712, 970]] 1.0 4wd5 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WD5B P00533 697 1016 1210.0 No_ligand No_ligand Inactive DFGinter 9.2476 4.4249 None -72.57, 139.36 -100.73, 10.04 -62.48, 143.44 260.7, 137.62 58.63, 39.1 in-out in 7.7295 Saltbr-out 3.7391 HRD-out -90.94, 114.01 -64.78, -40.5 out-out-out SNCooo out-out ActLoopNT-out 4.9778 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -60.44, 137.91 APE9-dihe-in -137.14, 159.08 APE8-dihe-in -84.32, 85.1 APE8-rot-na 36.97 APE67-dihe-in -61.6, -40.36 -63.96, -40.18 APE12-dist-na 16.5849 APE11-dist-na 15.8297 APE10-dist-na 16.9449 APE9-dist-out 8.8365 T790M None None XRAY 3.3 0.211 0.239 B 331.0 304.0 5 30 25 5 [[712, 970]] 1.0 4wd5 Homo sapiens TYR_EGFR_HUMAN TYR 8.4e-88 300.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name