PDB: 4U43 — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 4U43A
DFGout None 1 50.0% 4U43B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 4U43A O95819 14 311 1239.0 3D8:401 Type1 Inactive DFGin 4.1532 13.2791 BLBplus -128.02, 167.59 53.52, 51.18 -89.85, 159.42 63.11, 99.17 62.64, 20.89 in-in in 9.4481 Saltbr-in 3.1166 HRD-in -63.88, -52.19 81.86, -10.5 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -103.17, 129.4 APE9-dihe-na -73.75, -152.4 APE8-dihe-in -76.21, 141.15 APE8-rot-out 189.14 APE67-dihe-in -55.54, -27.45 -95.27, -11.48 APE12-dist-in 13.1305 APE11-dist-in 12.0937 APE10-dist-out 12.5275 APE9-dist-out 8.5145 None None None XRAY 2.18 0.199 0.242 A 332.0 287.0 11 28 17 11 [[25, 289]] 1.0 4u43 STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U43B O95819 10 311 1239.0 No_ligand No_ligand Inactive DFGout 16.2889 4.728 None -57.91, 126.01 -134.35, 92.48 -104.97, 41.66 281.52, 110.23 90.51, 59.66 out-out out 14.4356 Saltbr-out 13.0401 HRD-in -63.71, -51.88 82.9, -12.63 out-out-out SNCooo out-out ActLoopNT-out 6.9686 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -89.89, 129.63 APE9-dihe-na -74.53, -145.51 APE8-dihe-in -78.73, 137.83 APE8-rot-out 191.54 APE67-dihe-in -55.37, -28.59 -94.36, -10.33 APE12-dist-out 18.4658 APE11-dist-out 16.8971 APE10-dist-out 17.7292 APE9-dist-out 8.905 None None None XRAY 2.18 0.199 0.242 B 332.0 302.0 0 28 28 0 [[25, 289]] 1.0 4u43 STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 4U43 — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 4U43A
DFGout None 1 50.0% 4U43B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 4U43A O95819 14 311 1239.0 3D8:401 Type1 Inactive DFGin 4.1532 13.2791 BLBplus -128.02, 167.59 53.52, 51.18 -89.85, 159.42 63.11, 99.17 62.64, 20.89 in-in in 9.4481 Saltbr-in 3.1166 HRD-in -63.88, -52.19 81.86, -10.5 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -103.17, 129.4 APE9-dihe-na -73.75, -152.4 APE8-dihe-in -76.21, 141.15 APE8-rot-out 189.14 APE67-dihe-in -55.54, -27.45 -95.27, -11.48 APE12-dist-in 13.1305 APE11-dist-in 12.0937 APE10-dist-out 12.5275 APE9-dist-out 8.5145 None None None XRAY 2.18 0.199 0.242 A 332.0 287.0 11 28 17 11 [[25, 289]] 1.0 4u43 Homo sapiens STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U43B O95819 10 311 1239.0 No_ligand No_ligand Inactive DFGout 16.2889 4.728 None -57.91, 126.01 -134.35, 92.48 -104.97, 41.66 281.52, 110.23 90.51, 59.66 out-out out 14.4356 Saltbr-out 13.0401 HRD-in -63.71, -51.88 82.9, -12.63 out-out-out SNCooo out-out ActLoopNT-out 6.9686 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -89.89, 129.63 APE9-dihe-na -74.53, -145.51 APE8-dihe-in -78.73, 137.83 APE8-rot-out 191.54 APE67-dihe-in -55.37, -28.59 -94.36, -10.33 APE12-dist-out 18.4658 APE11-dist-out 16.8971 APE10-dist-out 17.7292 APE9-dist-out 8.905 None None None XRAY 2.18 0.199 0.242 B 332.0 302.0 0 28 28 0 [[25, 289]] 1.0 4u43 Homo sapiens STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 4U43 — STE M4K4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name