PDB: 4U40 — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 4U40A
DFGout None 1 50.0% 4U40B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 4U40A O95819 17 311 1239.0 ANP:401 ATPlike Inactive DFGin 3.8374 14.3902 BLBplus -136.79, 156.81 66.63, 45.06 -75.84, 145.72 56.03, 93.39 -61.09, 117.37 out-out out 11.6402 Saltbr-out 10.4893 HRD-in -68.35, -49.63 65.89, 2.04 out-out-out SNCooo out-out ActLoopNT-out 9.6283 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -76.11, -36.45 APE9-dihe-na 89.46, 175.41 APE8-dihe-in -63.67, 133.35 APE8-rot-out 188.73 APE67-dihe-in -61.71, -22.93 -96.09, -7.57 APE12-dist-out 14.8768 APE11-dist-out 14.965 APE10-dist-out 15.9776 APE9-dist-out 9.4768 None None None XRAY 2.3 0.201 0.262 A 332.0 295.0 0 28 28 0 [[25, 289]] 1.0 4u40 STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U40B O95819 13 311 1239.0 No_ligand No_ligand Inactive DFGout 16.9789 4.8603 None -58.33, 130.0 -140.04, 88.12 -92.84, 32.55 283.77, 110.6 100.78, 53.01 out-out out 15.1334 Saltbr-out 13.5311 HRD-in -74.7, -46.16 79.18, -17.97 out-out-out SNCooo out-out ActLoopNT-out 6.939 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -99.09, 129.36 APE9-dihe-na -87.21, -140.1 APE8-dihe-in -85.81, 130.5 APE8-rot-out 186.42 APE67-dihe-in -60.07, -29.15 -83.3, -16.35 APE12-dist-out 19.1266 APE11-dist-out 16.5875 APE10-dist-out 18.0955 APE9-dist-out 9.9159 None None None XRAY 2.3 0.201 0.262 B 332.0 299.0 0 28 28 0 [[25, 289]] 1.0 4u40 STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 4U40 — STE M4K4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 4U40A
DFGout None 1 50.0% 4U40B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP4K4 M4K4_HUMAN 4U40A O95819 17 311 1239.0 ANP:401 ATPlike Inactive DFGin 3.8374 14.3902 BLBplus -136.79, 156.81 66.63, 45.06 -75.84, 145.72 56.03, 93.39 -61.09, 117.37 out-out out 11.6402 Saltbr-out 10.4893 HRD-in -68.35, -49.63 65.89, 2.04 out-out-out SNCooo out-out ActLoopNT-out 9.6283 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -76.11, -36.45 APE9-dihe-na 89.46, 175.41 APE8-dihe-in -63.67, 133.35 APE8-rot-out 188.73 APE67-dihe-in -61.71, -22.93 -96.09, -7.57 APE12-dist-out 14.8768 APE11-dist-out 14.965 APE10-dist-out 15.9776 APE9-dist-out 9.4768 None None None XRAY 2.3 0.201 0.262 A 332.0 295.0 0 28 28 0 [[25, 289]] 1.0 4u40 Homo sapiens STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4
STE MAP4K4 M4K4_HUMAN 4U40B O95819 13 311 1239.0 No_ligand No_ligand Inactive DFGout 16.9789 4.8603 None -58.33, 130.0 -140.04, 88.12 -92.84, 32.55 283.77, 110.6 100.78, 53.01 out-out out 15.1334 Saltbr-out 13.5311 HRD-in -74.7, -46.16 79.18, -17.97 out-out-out SNCooo out-out ActLoopNT-out 6.939 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -99.09, 129.36 APE9-dihe-na -87.21, -140.1 APE8-dihe-in -85.81, 130.5 APE8-rot-out 186.42 APE67-dihe-in -60.07, -29.15 -83.3, -16.35 APE12-dist-out 19.1266 APE11-dist-out 16.5875 APE10-dist-out 18.0955 APE9-dist-out 9.9159 None None None XRAY 2.3 0.201 0.262 B 332.0 299.0 0 28 28 0 [[25, 289]] 1.0 4u40 Homo sapiens STE_MAP4K4_HUMAN STE 1.7e-102 348.1 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 Mitogen-activated protein kinase kinase kinase kinase 4

PDB: 4U40 — STE M4K4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name