4NIF

RPS6KA1 (Ribosomal protein S6 kinase alpha-1)
MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC CAMK
Uniprot: KS6A1_HUMAN MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 418 - 675 25 - 313
Resolution: 2.15

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A CAMK RPS6KA1 KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 Homo sapiens Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 413 - 728 3
D CAMK RPS6KA1 KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 Homo sapiens None DFGin BLAminus in-in in-none No_ligand No_ligand 413 - 728 3
B CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 Homo sapiens Inactive DFGin BLAminus in-in in-out ANP Type1 9 - 360 3
E CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 Homo sapiens Inactive DFGin BLAminus in-in in-out ANP Type1 10 - 360 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain E
         8         18         28         38 
gsmaaaaaag aGPEMVRGQV FDVGPRYTNL SYIGEGAYGM 
        48         58         68         78 
VCSAYDNVNK VRVAIKKISP FEHQTYCQRT LREIKILLRF 
        88         98        108        118 
RHENIIGIND IIRAPTIEQM KDVYIVQDLM ETDLYKLLKT 
       128        138        148        158 
QHLSNDHICY FLYQILRGLK YIHSANVLHR DLKPSNLLLN 
       168        178        188        198 
TTCDLKICDF GLARVADPDH dhtGFLTEYV ATRWYRAPEI 
       208        218        228        238 
MLNSKGYTKS IDIWSVGCIL AEMLSNRPIF PGKHYLDQLN 
       248        258        268        278 
HILGILGSPS QEDLNCIINL KARNYLLSLP HKNKVPWNRL 
       288        298        308        318 
FPNADSKALD LLDKMLTFNP HKRIEVEQAL AHPYLEQYYD 
       328        338        348        358 
PSDEPIAEAP FKFDMELDDL PKEKLKELIF EETARFQPGY 

RS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None