PDB: 4MNE — 2 kinases

Total number of chains: 8
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 50.0% 4MNEB
DFGin BLBplus 4 50.0% 4MNEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 4MNEA Q02750 63 379 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.3821 13.6901 BLBplus -140.61, 176.72 54.72, 28.13 -81.46, 161.59 52.56, 86.0 -81.78, 73.09 out-out out 15.4969 Saltbr-out 15.7793 HRD-in -64.01, -56.53 90.31, -35.13 out-out-out SNCooo out-out ActLoopNT-out 9.2902 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -73.66, 137.78 APE9-dihe-na -84.79, 178.97 APE8-dihe-out -113.02, -24.38 APE8-rot-out 49.94 APE67-dihe-out -153.46, 146.56 -142.39, -172.52 APE12-dist-out 17.192 APE11-dist-out 21.6533 APE10-dist-out 23.7976 APE9-dist-out 13.4974 None None None XRAY 2.848 0.186 0.24 A 341.0 286.0 31 26 26 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNED Q02750 66 382 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.2631 13.8726 BLBplus -124.78, 174.1 56.33, 33.25 -88.39, 154.28 50.46, 89.74 -73.02, 74.09 out-out out 15.5381 Saltbr-out 15.6141 HRD-in -64.9, -49.38 74.62, -12.51 out-out-out SNCooo out-out ActLoopNT-out 9.0432 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -65.65, 150.79 APE9-dihe-na -95.28, -163.25 APE8-dihe-out -122.75, -11.87 APE8-rot-out 68.42 APE67-dihe-out -159.06, 142.59 -161.08, -176.92 APE12-dist-out 17.403 APE11-dist-out 21.784 APE10-dist-out 23.8522 APE9-dist-out 13.6322 None None None XRAY 2.848 0.186 0.24 D 341.0 285.0 32 26 26 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEE Q02750 62 379 393.0 ACP:901,573:903 ATPlike,Type3 Inactive DFGin 6.3012 13.7407 BLBplus -139.17, 176.14 61.58, 40.21 -96.23, 153.1 47.97, 96.35 -69.87, 64.71 out-out out 15.7956 Saltbr-out 16.1573 HRD-in -84.17, -39.22 69.48, -27.4 out-out-out SNCooo out-out ActLoopNT-out 9.2771 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -76.04, 124.0 APE9-dihe-na -78.04, -178.79 APE8-dihe-out -111.0, -36.1 APE8-rot-out 69.56 APE67-dihe-out -140.43, 146.63 -132.48, 167.21 APE12-dist-out 17.6629 APE11-dist-out 21.7751 APE10-dist-out 24.2369 APE9-dist-out 13.5531 None None None XRAY 2.848 0.186 0.24 E 341.0 286.0 32 26 26 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEH Q02750 66 380 393.0 ACP:901,573:903,573:904 ATPlike,Type3,Allosteric Inactive DFGin 6.3776 13.8909 BLBplus -149.03, 175.24 52.75, 36.33 -93.4, 157.98 53.98, 84.28 -78.54, 56.84 out-out out 15.8147 Saltbr-out 15.4559 HRD-in -72.48, -51.28 80.05, -1.12 out-out-out SNCooo out-out ActLoopNT-out 9.1113 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.87, 146.83 APE9-dihe-na -98.86, 164.39 APE8-dihe-out -71.61, -59.39 APE8-rot-in 294.12 APE67-dihe-out -156.42, 156.79 -128.0, -169.25 APE12-dist-out 17.7474 APE11-dist-out 21.8877 APE10-dist-out 24.1565 APE9-dist-out 13.6645 None None None XRAY 2.848 0.186 0.24 H 341.0 275.0 40 26 26 0 [[68, 361]] 1.0 4mne STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 4MNEB P15056 449 722 766.0 No_ligand No_ligand Inactive DFGin 6.3822 14.1652 BLAminus -125.74, -157.34 46.68, 85.76 -102.98, 25.57 282.33, 63.28 -59.91, -20.47 in-in in 8.8119 Saltbr-in 3.0145 HRD-in -72.72, -45.6 70.84, -1.11 in-in-out SNCiio in-out ActLoopNT-in 2.8637 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -136.48, 156.53 APE9-dihe-na 140.48, 169.17 APE8-dihe-in -83.53, 130.6 APE8-rot-in 280.97 APE67-dihe-in -60.93, -19.54 -69.93, -34.89 APE12-dist-in 12.0056 APE11-dist-in 11.4713 APE10-dist-out 8.1118 APE9-dist-in 5.6075 None None None XRAY 2.848 0.186 0.24 B 308.0 270.0 4 30 30 0 [[457, 716]] 1.0 4mne TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEC P15056 449 720 766.0 No_ligand No_ligand Active DFGin 6.3096 14.1268 BLAminus -116.31, -150.46 30.76, 90.61 -104.11, 27.82 277.24, 67.68 -70.79, -9.9 in-in in 8.744 Saltbr-in 2.4391 HRD-in -70.5, -40.5 60.78, 9.72 in-in-in SNCiii in-in ActLoopNT-in 2.8085 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.23, 133.86 APE9-dihe-na 149.56, -167.49 APE8-dihe-in -112.25, 121.13 APE8-rot-in 303.71 APE67-dihe-in -62.07, -20.02 -56.34, -38.04 APE12-dist-in 12.1587 APE11-dist-in 11.5563 APE10-dist-in 7.5096 APE9-dist-in 5.815 None None None XRAY 2.848 0.186 0.24 C 308.0 260.0 12 30 23 7 [[457, 716]] 1.0 4mne TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEF P15056 449 721 766.0 No_ligand No_ligand Active DFGin 6.4761 13.7455 BLAminus -130.3, -157.72 45.09, 83.38 -99.59, 25.57 282.18, 62.71 -60.3, -26.4 in-in in 8.6846 Saltbr-in 2.75 HRD-in -78.22, -41.28 65.37, 2.99 in-in-in SNCiii in-in ActLoopNT-in 2.8744 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.88, 144.35 APE9-dihe-na 131.47, -165.54 APE8-dihe-in -107.46, 126.01 APE8-rot-in 299.7 APE67-dihe-in -57.35, -35.84 -68.63, -28.44 APE12-dist-in 12.5277 APE11-dist-in 11.9878 APE10-dist-in 7.5163 APE9-dist-in 5.8745 None None None XRAY 2.848 0.186 0.24 F 308.0 258.0 15 30 21 9 [[457, 716]] 1.0 4mne TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEG P15056 449 720 766.0 No_ligand No_ligand Inactive DFGin 6.3509 14.0054 BLAminus -133.48, -159.53 39.44, 81.15 -97.21, 35.04 282.93, 67.03 -73.28, -12.15 in-in in 8.9791 Saltbr-in 2.5708 HRD-in -72.6, -50.8 70.28, 6.2 in-in-out SNCiio in-out ActLoopNT-in 2.8807 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -151.59, 152.98 APE9-dihe-na 137.55, -171.6 APE8-dihe-in -109.27, 119.72 APE8-rot-in 306.4 APE67-dihe-in -64.78, -21.88 -56.06, -36.62 APE12-dist-in 12.0287 APE11-dist-in 11.4778 APE10-dist-out 8.0561 APE9-dist-in 5.6742 None None None XRAY 2.848 0.186 0.24 G 308.0 259.0 13 30 22 8 [[457, 716]] 1.0 4mne TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 4MNE — 2 kinases

Total number of chains: 8
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 50.0% 4MNEB
DFGin BLBplus 4 50.0% 4MNEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 4MNEA Q02750 63 379 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.3821 13.6901 BLBplus -140.61, 176.72 54.72, 28.13 -81.46, 161.59 52.56, 86.0 -81.78, 73.09 out-out out 15.4969 Saltbr-out 15.7793 HRD-in -64.01, -56.53 90.31, -35.13 out-out-out SNCooo out-out ActLoopNT-out 9.2902 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -73.66, 137.78 APE9-dihe-na -84.79, 178.97 APE8-dihe-out -113.02, -24.38 APE8-rot-out 49.94 APE67-dihe-out -153.46, 146.56 -142.39, -172.52 APE12-dist-out 17.192 APE11-dist-out 21.6533 APE10-dist-out 23.7976 APE9-dist-out 13.4974 None None None XRAY 2.848 0.186 0.24 A 341.0 286.0 31 26 26 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNED Q02750 66 382 393.0 ACP:901,573:903 ATPlike,Type1 Inactive DFGin 6.2631 13.8726 BLBplus -124.78, 174.1 56.33, 33.25 -88.39, 154.28 50.46, 89.74 -73.02, 74.09 out-out out 15.5381 Saltbr-out 15.6141 HRD-in -64.9, -49.38 74.62, -12.51 out-out-out SNCooo out-out ActLoopNT-out 9.0432 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -65.65, 150.79 APE9-dihe-na -95.28, -163.25 APE8-dihe-out -122.75, -11.87 APE8-rot-out 68.42 APE67-dihe-out -159.06, 142.59 -161.08, -176.92 APE12-dist-out 17.403 APE11-dist-out 21.784 APE10-dist-out 23.8522 APE9-dist-out 13.6322 None None None XRAY 2.848 0.186 0.24 D 341.0 285.0 32 26 26 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEE Q02750 62 379 393.0 ACP:901,573:903 ATPlike,Type3 Inactive DFGin 6.3012 13.7407 BLBplus -139.17, 176.14 61.58, 40.21 -96.23, 153.1 47.97, 96.35 -69.87, 64.71 out-out out 15.7956 Saltbr-out 16.1573 HRD-in -84.17, -39.22 69.48, -27.4 out-out-out SNCooo out-out ActLoopNT-out 9.2771 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -76.04, 124.0 APE9-dihe-na -78.04, -178.79 APE8-dihe-out -111.0, -36.1 APE8-rot-out 69.56 APE67-dihe-out -140.43, 146.63 -132.48, 167.21 APE12-dist-out 17.6629 APE11-dist-out 21.7751 APE10-dist-out 24.2369 APE9-dist-out 13.5531 None None None XRAY 2.848 0.186 0.24 E 341.0 286.0 32 26 26 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 4MNEH Q02750 66 380 393.0 ACP:901,573:903,573:904 ATPlike,Type3,Allosteric Inactive DFGin 6.3776 13.8909 BLBplus -149.03, 175.24 52.75, 36.33 -93.4, 157.98 53.98, 84.28 -78.54, 56.84 out-out out 15.8147 Saltbr-out 15.4559 HRD-in -72.48, -51.28 80.05, -1.12 out-out-out SNCooo out-out ActLoopNT-out 9.1113 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -63.87, 146.83 APE9-dihe-na -98.86, 164.39 APE8-dihe-out -71.61, -59.39 APE8-rot-in 294.12 APE67-dihe-out -156.42, 156.79 -128.0, -169.25 APE12-dist-out 17.7474 APE11-dist-out 21.8877 APE10-dist-out 24.1565 APE9-dist-out 13.6645 None None None XRAY 2.848 0.186 0.24 H 341.0 275.0 40 26 26 0 [[68, 361]] 1.0 4mne Homo sapiens STE_MAP2K1_HUMAN STE 1.5e-97 331.9 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 4MNEB P15056 449 722 766.0 No_ligand No_ligand Inactive DFGin 6.3822 14.1652 BLAminus -125.74, -157.34 46.68, 85.76 -102.98, 25.57 282.33, 63.28 -59.91, -20.47 in-in in 8.8119 Saltbr-in 3.0145 HRD-in -72.72, -45.6 70.84, -1.11 in-in-out SNCiio in-out ActLoopNT-in 2.8637 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -136.48, 156.53 APE9-dihe-na 140.48, 169.17 APE8-dihe-in -83.53, 130.6 APE8-rot-in 280.97 APE67-dihe-in -60.93, -19.54 -69.93, -34.89 APE12-dist-in 12.0056 APE11-dist-in 11.4713 APE10-dist-out 8.1118 APE9-dist-in 5.6075 None None None XRAY 2.848 0.186 0.24 B 308.0 270.0 4 30 30 0 [[457, 716]] 1.0 4mne Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEC P15056 449 720 766.0 No_ligand No_ligand Active DFGin 6.3096 14.1268 BLAminus -116.31, -150.46 30.76, 90.61 -104.11, 27.82 277.24, 67.68 -70.79, -9.9 in-in in 8.744 Saltbr-in 2.4391 HRD-in -70.5, -40.5 60.78, 9.72 in-in-in SNCiii in-in ActLoopNT-in 2.8085 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.23, 133.86 APE9-dihe-na 149.56, -167.49 APE8-dihe-in -112.25, 121.13 APE8-rot-in 303.71 APE67-dihe-in -62.07, -20.02 -56.34, -38.04 APE12-dist-in 12.1587 APE11-dist-in 11.5563 APE10-dist-in 7.5096 APE9-dist-in 5.815 None None None XRAY 2.848 0.186 0.24 C 308.0 260.0 12 30 23 7 [[457, 716]] 1.0 4mne Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEF P15056 449 721 766.0 No_ligand No_ligand Active DFGin 6.4761 13.7455 BLAminus -130.3, -157.72 45.09, 83.38 -99.59, 25.57 282.18, 62.71 -60.3, -26.4 in-in in 8.6846 Saltbr-in 2.75 HRD-in -78.22, -41.28 65.37, 2.99 in-in-in SNCiii in-in ActLoopNT-in 2.8744 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.88, 144.35 APE9-dihe-na 131.47, -165.54 APE8-dihe-in -107.46, 126.01 APE8-rot-in 299.7 APE67-dihe-in -57.35, -35.84 -68.63, -28.44 APE12-dist-in 12.5277 APE11-dist-in 11.9878 APE10-dist-in 7.5163 APE9-dist-in 5.8745 None None None XRAY 2.848 0.186 0.24 F 308.0 258.0 15 30 21 9 [[457, 716]] 1.0 4mne Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4MNEG P15056 449 720 766.0 No_ligand No_ligand Inactive DFGin 6.3509 14.0054 BLAminus -133.48, -159.53 39.44, 81.15 -97.21, 35.04 282.93, 67.03 -73.28, -12.15 in-in in 8.9791 Saltbr-in 2.5708 HRD-in -72.6, -50.8 70.28, 6.2 in-in-out SNCiio in-out ActLoopNT-in 2.8807 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -151.59, 152.98 APE9-dihe-na 137.55, -171.6 APE8-dihe-in -109.27, 119.72 APE8-rot-in 306.4 APE67-dihe-in -64.78, -21.88 -56.06, -36.62 APE12-dist-in 12.0287 APE11-dist-in 11.4778 APE10-dist-out 8.0561 APE9-dist-in 5.6742 None None None XRAY 2.848 0.186 0.24 G 308.0 259.0 13 30 22 8 [[457, 716]] 1.0 4mne Homo sapiens TKL_BRAF_HUMAN TKL 1.1e-81 280.3 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 4MNE — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name