PDB: 4E3C — OTHER IKKB_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% 4E3CB
DFGin None 2 33.3% 4E3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER IKBKB IKKB_HUMAN 4E3CB O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7231 12.4163 BLAminus -105.72, -155.63 -11.15, 130.65 -122.44, 23.83 259.84, 47.47 -53.22, -19.06 in-in in 8.4721 Saltbr-in 2.7706 HRD-in -75.6, -33.93 66.41, -70.8 in-in-out SNCiio in-out ActLoopNT-in 2.8748 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_iooo APE10-dihe-na -41.33, 120.77 APE9-dihe-na 145.43, -135.28 APE8-dihe-in -71.19, 72.96 APE8-rot-in 313.16 APE67-dihe-out 41.01, -82.54 -50.74, -88.53 APE12-dist-in 8.1682 APE11-dist-out 7.7771 APE10-dist-out 11.4687 APE9-dist-out 12.7616 S177E,S181E None None XRAY 3.98 0.267 0.299 B 669.0 632.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CC O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7051 12.3482 BLAminus -106.09, -155.19 -11.21, 130.09 -121.05, 26.29 258.84, 49.2 -40.6, -84.85 in-in in 8.4622 Saltbr-in 2.7612 HRD-in -71.79, -36.13 68.15, -71.55 in-in-out SNCiio in-out ActLoopNT-in 2.6523 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -85.59, 121.05 APE9-dihe-na 114.45, 160.33 APE8-dihe-out -45.72, -30.46 APE8-rot-out 41.29 APE67-dihe-out -70.56, -0.85 47.27, 14.31 APE12-dist-in 8.1115 APE11-dist-in 10.92 APE10-dist-out 8.1558 APE9-dist-out 11.1496 S177E,S181E None None XRAY 3.98 0.267 0.299 C 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CD O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7967 12.4624 BLAminus -105.23, -154.26 -12.01, 129.89 -121.15, 31.39 257.96, 46.78 -48.12, -73.54 in-in in 8.4714 Saltbr-in 2.7476 HRD-in -71.85, -36.56 68.87, -68.74 in-in-out SNCiio in-out ActLoopNT-in 2.7073 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -114.45, 136.63 APE9-dihe-na 128.45, -179.44 APE8-dihe-in -65.09, 82.14 APE8-rot-in 325.06 APE67-dihe-in -46.95, -54.94 -65.9, -0.17 APE12-dist-out 6.6721 APE11-dist-in 10.406 APE10-dist-out 10.2423 APE9-dist-out 11.628 S177E,S181E None None XRAY 3.98 0.267 0.299 D 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CF O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.6959 12.4712 BLAminus -105.36, -154.55 -11.85, 129.86 -122.15, 25.59 260.49, 46.17 -49.15, -47.61 in-in in 8.513 Saltbr-in 2.7733 HRD-in -73.41, -32.98 66.19, -71.94 in-in-out SNCiio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -67.61, 80.78 APE9-dihe-na 112.37, -167.24 APE8-dihe-in -59.27, 163.67 APE8-rot-in 314.68 APE67-dihe-in -41.53, -27.23 -138.25, 21.39 APE12-dist-in 9.3987 APE11-dist-in 9.604 APE10-dist-out 8.5263 APE9-dist-out 13.0124 S177E,S181E None None XRAY 3.98 0.267 0.299 F 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CA O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.9293 12.5145 None -102.89, -152.86 -13.03, 129.81 -123.22, 17.82 259.81, 46.81 -50.25, -6.57 in-in in 8.4978 Saltbr-in 2.7367 HRD-in -75.26, -33.92 66.88, -70.59 in-in-out SNCiio in-out ActLoopNT-in 2.667 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na 54.47, 176.72 APE9-dihe-na 61.59, 168.61 APE8-dihe-out -55.76, -20.8 APE8-rot-out 96.27 APE67-dihe-out -19.53, -58.21 71.19, -31.91 APE12-dist-in 7.8908 APE11-dist-in 11.3832 APE10-dist-out 9.7094 APE9-dist-out 11.5196 S177E,S181E None None XRAY 3.98 0.267 0.299 A 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CE O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.9501 12.2838 None -103.98, -153.14 -13.07, 129.81 -119.97, 29.25 259.42, 48.55 -39.7, -60.66 in-in in 8.4922 Saltbr-in 2.789 HRD-in -74.27, -34.04 66.66, -69.45 in-in-out SNCiio in-out ActLoopNT-in 2.7665 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -137.36, 34.73 APE9-dihe-na -147.47, 29.61 APE8-dihe-out 50.03, 13.62 APE8-rot-out 70.79 APE67-dihe-out 72.17, -45.62 58.67, -106.57 APE12-dist-in 7.8793 APE11-dist-in 9.547 APE10-dist-out 9.1157 APE9-dist-out 10.7947 S177E,S181E None None XRAY 3.98 0.267 0.299 E 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta

PDB: 4E3C — OTHER IKKB_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 66.7% 4E3CB
DFGin None 2 33.3% 4E3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER IKBKB IKKB_HUMAN 4E3CB O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7231 12.4163 BLAminus -105.72, -155.63 -11.15, 130.65 -122.44, 23.83 259.84, 47.47 -53.22, -19.06 in-in in 8.4721 Saltbr-in 2.7706 HRD-in -75.6, -33.93 66.41, -70.8 in-in-out SNCiio in-out ActLoopNT-in 2.8748 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_iooo APE10-dihe-na -41.33, 120.77 APE9-dihe-na 145.43, -135.28 APE8-dihe-in -71.19, 72.96 APE8-rot-in 313.16 APE67-dihe-out 41.01, -82.54 -50.74, -88.53 APE12-dist-in 8.1682 APE11-dist-out 7.7771 APE10-dist-out 11.4687 APE9-dist-out 12.7616 S177E,S181E None None XRAY 3.98 0.267 0.299 B 669.0 632.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CC O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7051 12.3482 BLAminus -106.09, -155.19 -11.21, 130.09 -121.05, 26.29 258.84, 49.2 -40.6, -84.85 in-in in 8.4622 Saltbr-in 2.7612 HRD-in -71.79, -36.13 68.15, -71.55 in-in-out SNCiio in-out ActLoopNT-in 2.6523 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -85.59, 121.05 APE9-dihe-na 114.45, 160.33 APE8-dihe-out -45.72, -30.46 APE8-rot-out 41.29 APE67-dihe-out -70.56, -0.85 47.27, 14.31 APE12-dist-in 8.1115 APE11-dist-in 10.92 APE10-dist-out 8.1558 APE9-dist-out 11.1496 S177E,S181E None None XRAY 3.98 0.267 0.299 C 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CD O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.7967 12.4624 BLAminus -105.23, -154.26 -12.01, 129.89 -121.15, 31.39 257.96, 46.78 -48.12, -73.54 in-in in 8.4714 Saltbr-in 2.7476 HRD-in -71.85, -36.56 68.87, -68.74 in-in-out SNCiio in-out ActLoopNT-in 2.7073 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -114.45, 136.63 APE9-dihe-na 128.45, -179.44 APE8-dihe-in -65.09, 82.14 APE8-rot-in 325.06 APE67-dihe-in -46.95, -54.94 -65.9, -0.17 APE12-dist-out 6.6721 APE11-dist-in 10.406 APE10-dist-out 10.2423 APE9-dist-out 11.628 S177E,S181E None None XRAY 3.98 0.267 0.299 D 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CF O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.6959 12.4712 BLAminus -105.36, -154.55 -11.85, 129.86 -122.15, 25.59 260.49, 46.17 -49.15, -47.61 in-in in 8.513 Saltbr-in 2.7733 HRD-in -73.41, -32.98 66.19, -71.94 in-in-out SNCiio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -67.61, 80.78 APE9-dihe-na 112.37, -167.24 APE8-dihe-in -59.27, 163.67 APE8-rot-in 314.68 APE67-dihe-in -41.53, -27.23 -138.25, 21.39 APE12-dist-in 9.3987 APE11-dist-in 9.604 APE10-dist-out 8.5263 APE9-dist-out 13.0124 S177E,S181E None None XRAY 3.98 0.267 0.299 F 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CA O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.9293 12.5145 None -102.89, -152.86 -13.03, 129.81 -123.22, 17.82 259.81, 46.81 -50.25, -6.57 in-in in 8.4978 Saltbr-in 2.7367 HRD-in -75.26, -33.92 66.88, -70.59 in-in-out SNCiio in-out ActLoopNT-in 2.667 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na 54.47, 176.72 APE9-dihe-na 61.59, 168.61 APE8-dihe-out -55.76, -20.8 APE8-rot-out 96.27 APE67-dihe-out -19.53, -58.21 71.19, -31.91 APE12-dist-in 7.8908 APE11-dist-in 11.3832 APE10-dist-out 9.7094 APE9-dist-out 11.5196 S177E,S181E None None XRAY 3.98 0.267 0.299 A 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER IKBKB IKKB_HUMAN 4E3CE O14920 16 665 756.0 No_ligand No_ligand Inactive DFGin 7.9501 12.2838 None -103.98, -153.14 -13.07, 129.81 -119.97, 29.25 259.42, 48.55 -39.7, -60.66 in-in in 8.4922 Saltbr-in 2.789 HRD-in -74.27, -34.04 66.66, -69.45 in-in-out SNCiio in-out ActLoopNT-in 2.7665 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -137.36, 34.73 APE9-dihe-na -147.47, 29.61 APE8-dihe-out 50.03, 13.62 APE8-rot-out 70.79 APE67-dihe-out 72.17, -45.62 58.67, -106.57 APE12-dist-in 7.8793 APE11-dist-in 9.547 APE10-dist-out 9.1157 APE9-dist-out 10.7947 S177E,S181E None None XRAY 3.98 0.267 0.299 E 669.0 624.0 4 27 27 0 [[15, 449]] 1.0 4e3c Homo sapiens OTHER_IKBKB_HUMAN OTHER 2.4e-50 178.4 1.0 249.0 249.0 165 166 167 169 171 44 61 65 142 144 143 145.0 204 192 187 186 185 184 183 182 181 97 Inhibitor of nuclear factor kappa-B kinase subunit beta

PDB: 4E3C — OTHER IKKB_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name