PDB: 4CXA — CMGC CDK12_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4CXAC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK12 CDK12_HUMAN 4CXAA 3.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 718 - 1050 0 TPO893 None Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 4CXAC 3.15 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 718 - 1048 0 TPO893 None Cyclin-dependent kinase 12

PDB: 4CXA — CMGC CDK12_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4CXAC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK12 CDK12_HUMAN 4CXAA 3.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 718 - 1050 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 4CXAC 3.15 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 718 - 1048 0 TPO893 None Cyclin-dependent kinase 12 Homo sapiens

PDB: 4CXA — CMGC CDK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism