3E88

AKT2 (RAC-beta serine/threonine-protein kinase)
Group: AGC
Uniprot: AKT2_HUMAN
Organism: Homo sapiens
Domain boundary: 152 - 409
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in G96 Type1.5_Back 146 - 480 0
B Active DFGin BLAminus in-in in-in G96 Type1.5_Back 146 - 480 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       155        165        175        185 
KVTMNDFDYL KLLGKGTFGK VILVREKATG RYYAMKILRK 
       195        205        215        225 
EVIIAKDEVA HTVTESRVLQ NTRHPFLTAL KYAFQTHDRL 
       235        245        255        265 
CFVMEYANGG ELFFHLSRER VFTEERARFY GAEIVSALEY 
       275        285        295        305 
LHSRDVVYRD IKLENLMLDK DGHIKITDFG LCKEGISDGA 
       315        325        335        345 
TMKTFCGTPE YLAPEVLEDN DYGRAVDWWG LGVVMYEMMC 
       355        365        375        385 
GRLPFYNQDH ERLFELILME EIRFPRTLSP EAKSLLAGLL 
       395        405        415        425 
KKDPKQRLGG GPSDAKEVME HRFFLSINWQ DVVQKKLLPP 
       435        445        455        465 
FKPQVTSEVD TRYFDDEFTA QSITITppdr ydslglleld 
       475 
QRTHFPQFDY SASIR
Lower-case residues are disordered in structure.
Mutations: S474D
Phosphorylation: X309,X451