PDB: 2RF9 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2RF9A
DFGout None 1 50.0% 2RF9B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 2RF9A P00533 699 983 1210.0 No_ligand No_ligand Inactive DFGout 13.946 6.908 BBAminus -121.77, 171.61 -138.84, 149.59 -128.18, 33.73 287.89, 52.24 57.49, 26.72 out-none out 11.966 Saltbr-none 999.0 HRD-in -57.96, -48.51 81.96, -56.62 none-in-out SNCnio in-out ActLoopNT-in 3.15 ActLoopCT-out TYR APEdihe_ooiai APEdist_aaai APE10-dihe-out 170.52, -17.42 APE9-dihe-out 56.97, 109.88 APE8-dihe-in -40.66, 127.28 APE8-rot-na 329.03 APE67-dihe-in -45.77, -18.55 -54.08, -53.0 APE12-dist-na 999.0 APE11-dist-na 8.375 APE10-dist-na 10.766 APE9-dist-in 6.542 None None None XRAY 3.5 0.272 0.329 A 330 280 5 0 0 2 [[712, 970]] 1.0 2rf9 TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RF9B P00533 701 985 1210.0 No_ligand No_ligand Inactive DFGout 13.677 7.667 None -135.45, 135.37 -89.59, 173.5 -159.16, 36.83 280.02, 95.88 54.88, 39.47 out-none out 12.947 Saltbr-none 999.0 HRD-in -35.92, -46.42 73.77, -11.36 none-in-out SNCnio in-out ActLoopNT-in 3.076 ActLoopCT-out TYR APEdihe_ioiai APEdist_aaao APE10-dihe-in -82.18, 154.3 APE9-dihe-out -131.03, 36.1 APE8-dihe-in -91.14, 62.73 APE8-rot-na 345.67 APE67-dihe-in -51.39, -4.74 -69.87, -65.73 APE12-dist-na 999.0 APE11-dist-na 12.061 APE10-dist-na 8.253 APE9-dist-out 9.864 None None None XRAY 3.5 0.272 0.329 B 330 269 16 0 0 6 [[712, 970]] 1.0 2rf9 TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 2RF9 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2RF9A
DFGout None 1 50.0% 2RF9B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 2RF9A P00533 699 983 1210.0 No_ligand No_ligand Inactive DFGout 13.946 6.908 BBAminus -121.77, 171.61 -138.84, 149.59 -128.18, 33.73 287.89, 52.24 57.49, 26.72 out-none out 11.966 Saltbr-none 999.0 HRD-in -57.96, -48.51 81.96, -56.62 none-in-out SNCnio in-out ActLoopNT-in 3.15 ActLoopCT-out TYR APEdihe_ooiai APEdist_aaai APE10-dihe-out 170.52, -17.42 APE9-dihe-out 56.97, 109.88 APE8-dihe-in -40.66, 127.28 APE8-rot-na 329.03 APE67-dihe-in -45.77, -18.55 -54.08, -53.0 APE12-dist-na 999.0 APE11-dist-na 8.375 APE10-dist-na 10.766 APE9-dist-in 6.542 None None None XRAY 3.5 0.272 0.329 A 330 280 5 0 0 2 [[712, 970]] 1.0 2rf9 Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RF9B P00533 701 985 1210.0 No_ligand No_ligand Inactive DFGout 13.677 7.667 None -135.45, 135.37 -89.59, 173.5 -159.16, 36.83 280.02, 95.88 54.88, 39.47 out-none out 12.947 Saltbr-none 999.0 HRD-in -35.92, -46.42 73.77, -11.36 none-in-out SNCnio in-out ActLoopNT-in 3.076 ActLoopCT-out TYR APEdihe_ioiai APEdist_aaao APE10-dihe-in -82.18, 154.3 APE9-dihe-out -131.03, 36.1 APE8-dihe-in -91.14, 62.73 APE8-rot-na 345.67 APE67-dihe-in -51.39, -4.74 -69.87, -65.73 APE12-dist-na 999.0 APE11-dist-na 12.061 APE10-dist-na 8.253 APE9-dist-out 9.864 None None None XRAY 3.5 0.272 0.329 B 330 269 16 0 0 6 [[712, 970]] 1.0 2rf9 Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 2RF9 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name