Ligand: TBS

Total number of chains: 5
Active chains: 4
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 8QCDA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 1P5EA 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1P5EC 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CSNK2A1 CSK21_HUMAN 7QGEA 2.27 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 2 - 334 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6TLLA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS, TBS Type1, Allosteric 2 - 334 0 None None Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QCDA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 7 - 333 0 None C336S Casein kinase II subunit alpha'

Ligand: TBS

Total number of chains: 7
Active chains: 5
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 8QCDA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 1P5EA 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1P5EC 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 7QGEA 2.27 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 2 - 334 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 6TLLA 1.88 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS, TBS Type1, Allosteric 2 - 334 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A2 CSK22_HUMAN 8QCDA 1.03 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 7 - 333 0 None C336S Casein kinase II subunit alpha' Homo sapiens
CMGC ACK2 CSK2A_MAIZE 1J91A 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1J91B 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 2 - 328 0 None None Casein kinase II subunit alpha Zea mays

Ligand: TBS

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1J91A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC ACK2 CSK2A_MAIZE 1J91A 2.22 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TBS Type1 2 - 328 0 None None Casein kinase II subunit alpha Zea mays
CMGC ACK2 CSK2A_MAIZE 1J91B 2.22 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TBS Type1 2 - 328 0 None None Casein kinase II subunit alpha Zea mays