Ligand: TBS

Total number of chains: 5
Active chains: 4
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 8QCDA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1P5EA P24941 1 296 298.0 TBS:60301 Type1 Active DFGin 6.66 15.009 BLAminus -134.09, 174.42 61.34, 86.25 -103.57, 17.59 277.72, 74.26 -59.56, -33.53 in-in in 8.446 Saltbr-in 2.674 HRD-in -77.23, -55.8 76.04, 12.25 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -75.42, 162.63 APE9-dihe-na 83.55, 127.96 APE8-dihe-in -48.61, 129.88 APE8-rot-in 295.62 APE67-dihe-in -60.38, -24.79 -44.17, -46.98 APE12-dist-in 13.307 APE11-dist-in 12.314 APE10-dist-in 7.439 APE9-dist-in 3.186 None TPO160 TPO160 XRAY 2.22 0.229 0.257 A 299 296 0 0 0 0 [[4, 286]] 1.0 1p5e CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1P5EC P24941 1 296 298.0 TBS:60302 Type1 Active DFGin 6.636 15.127 BLAminus -138.76, 179.25 54.43, 79.27 -94.7, 19.86 280.45, 76.08 -62.71, -27.5 in-in in 8.582 Saltbr-in 2.729 HRD-in -86.27, -53.86 71.16, 5.43 in-in-in SNCiii in-in ActLoopNT-in 2.91 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -73.64, 170.31 APE9-dihe-na 70.48, 126.73 APE8-dihe-in -48.62, 130.16 APE8-rot-in 290.02 APE67-dihe-in -53.04, -25.69 -34.83, -58.58 APE12-dist-in 13.275 APE11-dist-in 12.466 APE10-dist-in 7.437 APE9-dist-in 3.204 None TPO160 TPO160 XRAY 2.22 0.229 0.257 C 299 296 0 0 0 0 [[4, 286]] 1.0 1p5e CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CSNK2A1 CSK21_HUMAN 7QGEA P68400 2 334 391.0 TBS:401 Type1 Active DFGin 7.478 16.247 BLAminus -115.29, 178.92 53.81, 80.69 -94.75, 16.33 294.68, 81.45 -70.2, -16.82 in-in in 9.271 Saltbr-in 2.745 HRD-in -75.41, -46.75 67.11, 14.09 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.06, 167.41 APE9-dihe-na 62.17, 167.27 APE8-dihe-in -93.07, 147.62 APE8-rot-in 308.3 APE67-dihe-in -69.0, -17.71 -35.98, -55.91 APE12-dist-in 12.719 APE11-dist-in 10.462 APE10-dist-in 6.289 APE9-dist-in 3.455 None None None XRAY 2.27 0.173 0.205 A 399 333 0 0 0 0 [[39, 324]] 1.0 7qge CMGC_CSNK2A1_HUMAN CMGC 2.4e-69 239.8 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6TLLA P68400 2 334 391.0 TBS:401,TBS:402 Type1,Allosteric Active DFGin 7.43 16.223 BLAminus -114.24, -178.85 53.06, 80.79 -92.78, 17.92 294.36, 83.01 -66.84, -24.11 in-in in 9.36 Saltbr-in 2.675 HRD-in -73.15, -50.87 71.72, 7.53 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.98, 168.63 APE9-dihe-na 66.43, 159.22 APE8-dihe-in -83.59, 147.35 APE8-rot-in 298.7 APE67-dihe-in -68.68, -16.27 -40.26, -54.89 APE12-dist-in 12.631 APE11-dist-in 10.36 APE10-dist-in 6.048 APE9-dist-in 3.475 None None None XRAY 1.88 0.161 0.187 A 399 333 0 0 0 0 [[39, 324]] 1.0 6tll CMGC_CSNK2A1_HUMAN CMGC 2.4e-69 239.8 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QCDA P19784 7 333 350.0 TBS:402 Type1 Inactive DFGin 7.384 16.126 BLAminus -114.5, 177.89 62.48, 71.57 -90.43, 15.0 296.22, 81.56 -72.45, -14.89 in-in in 9.456 Saltbr-in 2.787 HRD-in -74.09, -49.74 73.57, 10.6 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.12, 167.72 APE9-dihe-na 66.59, 156.6 APE8-dihe-in -73.54, 148.52 APE8-rot-out 150.56 APE67-dihe-in -71.43, -15.51 -42.4, -50.04 APE12-dist-in 12.556 APE11-dist-in 10.11 APE10-dist-in 6.138 APE9-dist-in 3.237 C336S None None XRAY 1.03 0.144 0.156 A 364 327 0 0 0 0 [[40, 325]] 1.0 8qcd CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: TBS

Total number of chains: 7
Active chains: 5
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 8QCDA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1P5EA P24941 1 296 298.0 TBS:60301 Type1 Active DFGin 6.66 15.009 BLAminus -134.09, 174.42 61.34, 86.25 -103.57, 17.59 277.72, 74.26 -59.56, -33.53 in-in in 8.446 Saltbr-in 2.674 HRD-in -77.23, -55.8 76.04, 12.25 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -75.42, 162.63 APE9-dihe-na 83.55, 127.96 APE8-dihe-in -48.61, 129.88 APE8-rot-in 295.62 APE67-dihe-in -60.38, -24.79 -44.17, -46.98 APE12-dist-in 13.307 APE11-dist-in 12.314 APE10-dist-in 7.439 APE9-dist-in 3.186 None TPO160 TPO160 XRAY 2.22 0.229 0.257 A 299 296 0 0 0 0 [[4, 286]] 1.0 1p5e Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1P5EC P24941 1 296 298.0 TBS:60302 Type1 Active DFGin 6.636 15.127 BLAminus -138.76, 179.25 54.43, 79.27 -94.7, 19.86 280.45, 76.08 -62.71, -27.5 in-in in 8.582 Saltbr-in 2.729 HRD-in -86.27, -53.86 71.16, 5.43 in-in-in SNCiii in-in ActLoopNT-in 2.91 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -73.64, 170.31 APE9-dihe-na 70.48, 126.73 APE8-dihe-in -48.62, 130.16 APE8-rot-in 290.02 APE67-dihe-in -53.04, -25.69 -34.83, -58.58 APE12-dist-in 13.275 APE11-dist-in 12.466 APE10-dist-in 7.437 APE9-dist-in 3.204 None TPO160 TPO160 XRAY 2.22 0.229 0.257 C 299 296 0 0 0 0 [[4, 286]] 1.0 1p5e Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CSNK2A1 CSK21_HUMAN 7QGEA P68400 2 334 391.0 TBS:401 Type1 Active DFGin 7.478 16.247 BLAminus -115.29, 178.92 53.81, 80.69 -94.75, 16.33 294.68, 81.45 -70.2, -16.82 in-in in 9.271 Saltbr-in 2.745 HRD-in -75.41, -46.75 67.11, 14.09 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.06, 167.41 APE9-dihe-na 62.17, 167.27 APE8-dihe-in -93.07, 147.62 APE8-rot-in 308.3 APE67-dihe-in -69.0, -17.71 -35.98, -55.91 APE12-dist-in 12.719 APE11-dist-in 10.462 APE10-dist-in 6.289 APE9-dist-in 3.455 None None None XRAY 2.27 0.173 0.205 A 399 333 0 0 0 0 [[39, 324]] 1.0 7qge Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 2.4e-69 239.8 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 6TLLA P68400 2 334 391.0 TBS:401,TBS:402 Type1,Allosteric Active DFGin 7.43 16.223 BLAminus -114.24, -178.85 53.06, 80.79 -92.78, 17.92 294.36, 83.01 -66.84, -24.11 in-in in 9.36 Saltbr-in 2.675 HRD-in -73.15, -50.87 71.72, 7.53 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.98, 168.63 APE9-dihe-na 66.43, 159.22 APE8-dihe-in -83.59, 147.35 APE8-rot-in 298.7 APE67-dihe-in -68.68, -16.27 -40.26, -54.89 APE12-dist-in 12.631 APE11-dist-in 10.36 APE10-dist-in 6.048 APE9-dist-in 3.475 None None None XRAY 1.88 0.161 0.187 A 399 333 0 0 0 0 [[39, 324]] 1.0 6tll Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 2.4e-69 239.8 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 8QCDA P19784 7 333 350.0 TBS:402 Type1 Inactive DFGin 7.384 16.126 BLAminus -114.5, 177.89 62.48, 71.57 -90.43, 15.0 296.22, 81.56 -72.45, -14.89 in-in in 9.456 Saltbr-in 2.787 HRD-in -74.09, -49.74 73.57, 10.6 in-in-out SNCiio in-out ActLoopNT-in 2.834 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.12, 167.72 APE9-dihe-na 66.59, 156.6 APE8-dihe-in -73.54, 148.52 APE8-rot-out 150.56 APE67-dihe-in -71.43, -15.51 -42.4, -50.04 APE12-dist-in 12.556 APE11-dist-in 10.11 APE10-dist-in 6.138 APE9-dist-in 3.237 C336S None None XRAY 1.03 0.144 0.156 A 364 327 0 0 0 0 [[40, 325]] 1.0 8qcd Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC ACK2 CSK2A_MAIZE 1J91A P28523 2 328 332.0 TBS:60338 Type1 Inactive DFGin 7.442 16.279 BLAminus -108.92, -179.95 52.22, 84.12 -96.61, 24.25 297.3, 73.98 -62.93, -23.29 in-in in 9.156 Saltbr-in 2.552 HRD-in -77.3, -49.44 69.47, 6.62 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.78, 169.11 APE9-dihe-na 68.89, -176.57 APE8-dihe-in -109.79, 146.07 APE8-rot-out 57.6 APE67-dihe-in -66.39, -13.48 -33.34, -55.36 APE12-dist-in 12.437 APE11-dist-in 10.114 APE10-dist-in 6.078 APE9-dist-in 3.123 None None None XRAY 2.22 0.205 0.268 A 332 327 0 0 0 0 [[34, 319]] 1.0 1j91 Zea mays CMGC_ACK2_MAIZE CMGC 1.8e-65 227.0 1 301 301 169 170 171 173 175 63 76 80 148 150 149 151 209 196 191 190 189 188 187 186 185 109 Casein kinase II subunit alpha
CMGC ACK2 CSK2A_MAIZE 1J91B P28523 2 328 332.0 TBS:60338 Type1 Active DFGin 7.306 16.422 BLAminus -104.35, -176.19 46.27, 85.58 -95.61, 24.08 297.43, 73.38 -67.02, -19.88 in-in in 9.513 Saltbr-in 2.728 HRD-in -76.84, -49.65 68.69, 10.18 in-in-in SNCiii in-in ActLoopNT-in 2.881 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.5, 167.92 APE9-dihe-na 69.48, -179.79 APE8-dihe-in -100.35, 146.47 APE8-rot-in 289.52 APE67-dihe-in -66.99, -16.16 -39.98, -51.79 APE12-dist-in 12.527 APE11-dist-in 10.183 APE10-dist-in 6.164 APE9-dist-in 3.127 None None None XRAY 2.22 0.205 0.268 B 332 327 0 0 0 0 [[34, 319]] 1.0 1j91 Zea mays CMGC_ACK2_MAIZE CMGC 1.8e-65 227.0 1 301 301 169 170 171 173 175 63 76 80 148 150 149 151 209 196 191 190 189 188 187 186 185 109 Casein kinase II subunit alpha

Ligand: TBS

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1J91A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC ACK2 CSK2A_MAIZE 1J91A P28523 2 328 332.0 TBS:60338 Type1 Inactive DFGin 7.442 16.279 BLAminus -108.92, -179.95 52.22, 84.12 -96.61, 24.25 297.3, 73.98 -62.93, -23.29 in-in in 9.156 Saltbr-in 2.552 HRD-in -77.3, -49.44 69.47, 6.62 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.78, 169.11 APE9-dihe-na 68.89, -176.57 APE8-dihe-in -109.79, 146.07 APE8-rot-out 57.6 APE67-dihe-in -66.39, -13.48 -33.34, -55.36 APE12-dist-in 12.437 APE11-dist-in 10.114 APE10-dist-in 6.078 APE9-dist-in 3.123 None None None XRAY 2.22 0.205 0.268 A 332 327 0 0 0 0 [[34, 319]] 1.0 1j91 Zea mays CMGC_ACK2_MAIZE CMGC 1.8e-65 227.0 1 301 301 169 170 171 173 175 63 76 80 148 150 149 151 209 196 191 190 189 188 187 186 185 109 Casein kinase II subunit alpha
CMGC ACK2 CSK2A_MAIZE 1J91B P28523 2 328 332.0 TBS:60338 Type1 Active DFGin 7.306 16.422 BLAminus -104.35, -176.19 46.27, 85.58 -95.61, 24.08 297.43, 73.38 -67.02, -19.88 in-in in 9.513 Saltbr-in 2.728 HRD-in -76.84, -49.65 68.69, 10.18 in-in-in SNCiii in-in ActLoopNT-in 2.881 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.5, 167.92 APE9-dihe-na 69.48, -179.79 APE8-dihe-in -100.35, 146.47 APE8-rot-in 289.52 APE67-dihe-in -66.99, -16.16 -39.98, -51.79 APE12-dist-in 12.527 APE11-dist-in 10.183 APE10-dist-in 6.164 APE9-dist-in 3.127 None None None XRAY 2.22 0.205 0.268 B 332 327 0 0 0 0 [[34, 319]] 1.0 1j91 Zea mays CMGC_ACK2_MAIZE CMGC 1.8e-65 227.0 1 301 301 169 170 171 173 175 63 76 80 148 150 149 151 209 196 191 190 189 188 187 186 185 109 Casein kinase II subunit alpha