Ligand: RFZ

Total number of chains: 5
Active chains: 5
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3H30B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 3MY5A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 1 - 298 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3MY5C 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 3MY1A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 3H30B 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 2 - 334 0 None None Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3H30A 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ, RFZ Type1, Allosteric 2 - 334 0 None None Casein kinase II subunit alpha

Ligand: RFZ

Total number of chains: 5
Active chains: 5
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3H30B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 3MY5A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 1 - 298 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3MY5C 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 1 - 296 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK9 CDK9_HUMAN 3MY1A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 6 - 327 0 TPO186 None Cyclin-dependent kinase 9 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3H30B 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ Type1 2 - 334 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 3H30A 1.56 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RFZ, RFZ Type1, Allosteric 2 - 334 0 None None Casein kinase II subunit alpha Homo sapiens

Ligand: RFZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism