Ligand: RFZ

Total number of chains: 5
Active chains: 5
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3H30B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3MY5A P24941 1 298 298.0 RFZ:60300 Type1 Active DFGin 6.667 15.3481 BLAminus -135.55, -178.04 53.6, 76.52 -97.01, 15.67 276.61, 75.78 -59.51, -26.48 in-in in 8.74 Saltbr-in 2.7654 HRD-in -79.62, -51.44 67.18, 13.09 in-in-in SNCiii in-in ActLoopNT-in 2.8831 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.67, 153.77 APE9-dihe-na 76.12, 127.46 APE8-dihe-in -56.8, 137.09 APE8-rot-in 303.01 APE67-dihe-in -62.09, -25.12 -50.14, -44.68 APE12-dist-in 13.1416 APE11-dist-in 10.346 APE10-dist-in 7.1077 APE9-dist-in 3.2426 None TPO160 TPO160 XRAY 2.1 0.182 0.219 A 300.0 295.0 3 28 28 0 [[4, 286]] 1.0 3my5 CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3MY5C P24941 1 296 298.0 RFZ:60301 Type1 Active DFGin 6.7203 15.3826 BLAminus -140.83, -171.85 49.57, 71.36 -87.98, 20.89 279.16, 71.11 -63.16, -26.32 in-in in 8.5992 Saltbr-in 2.6986 HRD-in -80.11, -52.55 69.91, 13.09 in-in-in SNCiii in-in ActLoopNT-in 2.9192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.93, 151.21 APE9-dihe-na 70.99, 122.72 APE8-dihe-in -51.33, 141.26 APE8-rot-in 307.41 APE67-dihe-in -61.95, -24.04 -45.65, -48.3 APE12-dist-in 12.7292 APE11-dist-in 9.8116 APE10-dist-in 6.8134 APE9-dist-in 3.2609 None TPO160 TPO160 XRAY 2.1 0.182 0.219 C 300.0 266.0 30 28 28 0 [[4, 286]] 1.0 3my5 CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 3MY1A P50750 6 327 372.0 RFZ:336 Type1 Active DFGin 6.9201 14.7372 BLAminus -138.6, -178.76 55.85, 82.27 -96.58, 26.19 286.18, 71.12 -65.01, -22.99 in-in in 9.1741 Saltbr-in 3.0243 HRD-in -74.76, -49.19 65.23, 25.42 in-in-in SNCiii in-in ActLoopNT-in 2.7707 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.34, 163.18 APE9-dihe-na 70.44, 131.12 APE8-dihe-in -41.78, 152.21 APE8-rot-in 296.57 APE67-dihe-in -62.52, -36.66 -60.91, -51.23 APE12-dist-in 13.127 APE11-dist-in 11.2204 APE10-dist-in 6.8527 APE9-dist-in 3.38 None TPO186 TPO186 XRAY 2.8 0.175 0.214 A 331.0 315.0 7 32 32 0 [[19, 315]] 1.0 3my1 CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 3H30B P68400 2 334 391.0 RFZ:336 Type1 Active DFGin 7.4557 16.0058 BLAminus -121.2, -177.83 50.16, 78.47 -91.32, 16.71 294.46, 81.2 -67.28, -17.25 in-in in 9.7544 Saltbr-in 2.8161 HRD-in -73.44, -46.19 70.73, 6.27 in-in-in SNCiii in-in ActLoopNT-in 2.9089 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.81, 161.54 APE9-dihe-na 72.36, 159.32 APE8-dihe-in -83.53, 154.64 APE8-rot-in 275.73 APE67-dihe-in -66.72, -16.57 -46.01, -48.92 APE12-dist-in 12.2206 APE11-dist-in 9.5564 APE10-dist-in 5.7146 APE9-dist-in 3.2406 None None None XRAY 1.56 0.157 0.198 B 334.0 333.0 0 27 27 0 [[39, 324]] 1.0 3h30 CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3H30A P68400 2 334 391.0 RFZ:336,RFZ:337 Type1,Allosteric Active DFGin 7.3054 16.0584 BLAminus -122.05, -178.36 67.26, 61.9 -89.53, 18.61 298.78, 84.71 -69.6, -23.95 in-in in 9.8423 Saltbr-in 2.9633 HRD-in -71.87, -53.95 70.9, 12.23 in-in-in SNCiii in-in ActLoopNT-in 2.7919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.59, 165.18 APE9-dihe-na 65.63, 145.84 APE8-dihe-in -78.59, 146.66 APE8-rot-in 306.03 APE67-dihe-in -67.49, -16.87 -42.57, -51.44 APE12-dist-in 12.5625 APE11-dist-in 9.6483 APE10-dist-in 6.2432 APE9-dist-in 3.2308 None None None XRAY 1.56 0.157 0.198 A 334.0 333.0 0 27 27 0 [[39, 324]] 1.0 3h30 CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha

Ligand: RFZ

Total number of chains: 5
Active chains: 5
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3H30B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3MY5A P24941 1 298 298.0 RFZ:60300 Type1 Active DFGin 6.667 15.3481 BLAminus -135.55, -178.04 53.6, 76.52 -97.01, 15.67 276.61, 75.78 -59.51, -26.48 in-in in 8.74 Saltbr-in 2.7654 HRD-in -79.62, -51.44 67.18, 13.09 in-in-in SNCiii in-in ActLoopNT-in 2.8831 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.67, 153.77 APE9-dihe-na 76.12, 127.46 APE8-dihe-in -56.8, 137.09 APE8-rot-in 303.01 APE67-dihe-in -62.09, -25.12 -50.14, -44.68 APE12-dist-in 13.1416 APE11-dist-in 10.346 APE10-dist-in 7.1077 APE9-dist-in 3.2426 None TPO160 TPO160 XRAY 2.1 0.182 0.219 A 300.0 295.0 3 28 28 0 [[4, 286]] 1.0 3my5 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3MY5C P24941 1 296 298.0 RFZ:60301 Type1 Active DFGin 6.7203 15.3826 BLAminus -140.83, -171.85 49.57, 71.36 -87.98, 20.89 279.16, 71.11 -63.16, -26.32 in-in in 8.5992 Saltbr-in 2.6986 HRD-in -80.11, -52.55 69.91, 13.09 in-in-in SNCiii in-in ActLoopNT-in 2.9192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.93, 151.21 APE9-dihe-na 70.99, 122.72 APE8-dihe-in -51.33, 141.26 APE8-rot-in 307.41 APE67-dihe-in -61.95, -24.04 -45.65, -48.3 APE12-dist-in 12.7292 APE11-dist-in 9.8116 APE10-dist-in 6.8134 APE9-dist-in 3.2609 None TPO160 TPO160 XRAY 2.1 0.182 0.219 C 300.0 266.0 30 28 28 0 [[4, 286]] 1.0 3my5 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 3MY1A P50750 6 327 372.0 RFZ:336 Type1 Active DFGin 6.9201 14.7372 BLAminus -138.6, -178.76 55.85, 82.27 -96.58, 26.19 286.18, 71.12 -65.01, -22.99 in-in in 9.1741 Saltbr-in 3.0243 HRD-in -74.76, -49.19 65.23, 25.42 in-in-in SNCiii in-in ActLoopNT-in 2.7707 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.34, 163.18 APE9-dihe-na 70.44, 131.12 APE8-dihe-in -41.78, 152.21 APE8-rot-in 296.57 APE67-dihe-in -62.52, -36.66 -60.91, -51.23 APE12-dist-in 13.127 APE11-dist-in 11.2204 APE10-dist-in 6.8527 APE9-dist-in 3.38 None TPO186 TPO186 XRAY 2.8 0.175 0.214 A 331.0 315.0 7 32 32 0 [[19, 315]] 1.0 3my1 Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1.0 301.0 301.0 166 167 168 170 172 48 66 70 146 148 147 149.0 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9
CMGC CSNK2A1 CSK21_HUMAN 3H30B P68400 2 334 391.0 RFZ:336 Type1 Active DFGin 7.4557 16.0058 BLAminus -121.2, -177.83 50.16, 78.47 -91.32, 16.71 294.46, 81.2 -67.28, -17.25 in-in in 9.7544 Saltbr-in 2.8161 HRD-in -73.44, -46.19 70.73, 6.27 in-in-in SNCiii in-in ActLoopNT-in 2.9089 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.81, 161.54 APE9-dihe-na 72.36, 159.32 APE8-dihe-in -83.53, 154.64 APE8-rot-in 275.73 APE67-dihe-in -66.72, -16.57 -46.01, -48.92 APE12-dist-in 12.2206 APE11-dist-in 9.5564 APE10-dist-in 5.7146 APE9-dist-in 3.2406 None None None XRAY 1.56 0.157 0.198 B 334.0 333.0 0 27 27 0 [[39, 324]] 1.0 3h30 Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3H30A P68400 2 334 391.0 RFZ:336,RFZ:337 Type1,Allosteric Active DFGin 7.3054 16.0584 BLAminus -122.05, -178.36 67.26, 61.9 -89.53, 18.61 298.78, 84.71 -69.6, -23.95 in-in in 9.8423 Saltbr-in 2.9633 HRD-in -71.87, -53.95 70.9, 12.23 in-in-in SNCiii in-in ActLoopNT-in 2.7919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.59, 165.18 APE9-dihe-na 65.63, 145.84 APE8-dihe-in -78.59, 146.66 APE8-rot-in 306.03 APE67-dihe-in -67.49, -16.87 -42.57, -51.44 APE12-dist-in 12.5625 APE11-dist-in 9.6483 APE10-dist-in 6.2432 APE9-dist-in 3.2308 None None None XRAY 1.56 0.157 0.198 A 334.0 333.0 0 27 27 0 [[39, 324]] 1.0 3h30 Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha

Ligand: RFZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name