Ligand: R09

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 4USEA
DFGout None 2 50.0% 4USDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE STK10 STK10_HUMAN 4USEA O94804 24 316 968.0 R09:500 Type1 Inactive DFGin 6.6667 16.3125 ABAminus -124.06, -47.73 -111.47, 110.64 -107.37, 33.1 286.3, 80.35 -74.02, -29.24 in-out in 9.8746 Saltbr-out 5.3841 HRD-in -76.52, -50.26 63.76, 8.26 out-out-out SNCooo out-out ActLoopNT-out 5.8803 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.21 APE8-rot-in 292.58 APE67-dihe-out -68.99, -19.32 -97.26, 50.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.226 0.251 A 302.0 286.0 7 28 21 7 [[36, 294]] 1.0 4use STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USEB O94804 24 316 968.0 R09:500 Type1 Inactive DFGin 6.6724 16.3943 ABAminus -123.54, -48.03 -110.84, 111.05 -107.61, 33.16 286.69, 80.16 -75.08, -28.62 in-out in 9.8936 Saltbr-out 5.3583 HRD-in -76.02, -50.04 64.2, 8.63 out-out-out SNCooo out-out ActLoopNT-out 5.8892 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -53.4 APE8-rot-in 294.34 APE67-dihe-out -69.37, -18.81 -96.21, 50.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.226 0.251 B 302.0 278.0 15 28 22 6 [[36, 294]] 1.0 4use STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USDA O94804 24 314 968.0 R09:500 Type1 Inactive DFGout 15.9829 6.513 None -127.04, 147.35 -89.99, -48.64 52.66, 44.35 201.48, 52.81 133.39, -8.64 out-out out 11.4741 Saltbr-out 7.2191 HRD-in -98.1, -42.18 72.73, 6.06 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 14.27 APE8-dihe-in -75.81, 156.02 APE8-rot-in 326.25 APE67-dihe-out -84.4, -25.55 -131.98, 90.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8547 None None None XRAY 3.05 0.237 0.289 A 302.0 268.0 23 28 13 15 [[36, 294]] 1.0 4usd STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USDB O94804 24 314 968.0 R09:500 Type1 Inactive DFGout 15.9322 6.4737 None -127.63, 146.51 -89.68, -49.09 53.05, 44.03 201.59, 52.69 133.19, -10.34 out-out out 11.4851 Saltbr-out 7.256 HRD-in -95.04, -42.77 73.11, 4.97 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 15.7 APE8-dihe-in -74.23, 153.57 APE8-rot-in 331.06 APE67-dihe-out -82.52, -24.09 -130.17, 87.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8703 None None None XRAY 3.05 0.237 0.289 B 302.0 267.0 24 28 13 15 [[36, 294]] 1.0 4usd STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10

Ligand: R09

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 4USEA
DFGout None 2 50.0% 4USDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE STK10 STK10_HUMAN 4USEA O94804 24 316 968.0 R09:500 Type1 Inactive DFGin 6.6667 16.3125 ABAminus -124.06, -47.73 -111.47, 110.64 -107.37, 33.1 286.3, 80.35 -74.02, -29.24 in-out in 9.8746 Saltbr-out 5.3841 HRD-in -76.52, -50.26 63.76, 8.26 out-out-out SNCooo out-out ActLoopNT-out 5.8803 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -51.21 APE8-rot-in 292.58 APE67-dihe-out -68.99, -19.32 -97.26, 50.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.226 0.251 A 302.0 286.0 7 28 21 7 [[36, 294]] 1.0 4use Homo sapiens STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USEB O94804 24 316 968.0 R09:500 Type1 Inactive DFGin 6.6724 16.3943 ABAminus -123.54, -48.03 -110.84, 111.05 -107.61, 33.16 286.69, 80.16 -75.08, -28.62 in-out in 9.8936 Saltbr-out 5.3583 HRD-in -76.02, -50.04 64.2, 8.63 out-out-out SNCooo out-out ActLoopNT-out 5.8892 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -53.4 APE8-rot-in 294.34 APE67-dihe-out -69.37, -18.81 -96.21, 50.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.65 0.226 0.251 B 302.0 278.0 15 28 22 6 [[36, 294]] 1.0 4use Homo sapiens STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USDA O94804 24 314 968.0 R09:500 Type1 Inactive DFGout 15.9829 6.513 None -127.04, 147.35 -89.99, -48.64 52.66, 44.35 201.48, 52.81 133.39, -8.64 out-out out 11.4741 Saltbr-out 7.2191 HRD-in -98.1, -42.18 72.73, 6.06 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 14.27 APE8-dihe-in -75.81, 156.02 APE8-rot-in 326.25 APE67-dihe-out -84.4, -25.55 -131.98, 90.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8547 None None None XRAY 3.05 0.237 0.289 A 302.0 268.0 23 28 13 15 [[36, 294]] 1.0 4usd Homo sapiens STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 4USDB O94804 24 314 968.0 R09:500 Type1 Inactive DFGout 15.9322 6.4737 None -127.63, 146.51 -89.68, -49.09 53.05, 44.03 201.59, 52.69 133.19, -10.34 out-out out 11.4851 Saltbr-out 7.256 HRD-in -95.04, -42.77 73.11, 4.97 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 15.7 APE8-dihe-in -74.23, 153.57 APE8-rot-in 331.06 APE67-dihe-out -82.52, -24.09 -130.17, 87.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.8703 None None None XRAY 3.05 0.237 0.289 B 302.0 267.0 24 28 13 15 [[36, 294]] 1.0 4usd Homo sapiens STE_STK10_HUMAN STE 2e-94 321.6 1.0 257.0 257.0 174 175 176 178 180 65 81 85 154 156 155 157.0 219 202 197 196 195 194 193 192 191 111 Serine/threonine-protein kinase 10

Ligand: R09

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name