Ligand: QP1

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 60.0% 6V66A
DFGin BLAminus 1 20.0% 6VHPA
DFGin BLBplus 1 20.0% 6V66D

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai QP1 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QP1 Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor

Ligand: QP1

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 60.0% 6V66A
DFGin BLAminus 1 20.0% 6VHPA
DFGin BLBplus 1 20.0% 6V66D

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai QP1 Type1 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QP1 Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: QP1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism