Ligand: OXW

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 6YLCB
DFGinter None 1 25.0% 6YLCD
DFGout None 1 25.0% 6YLCA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK6 MK06_HUMAN 6YLCB 2.43 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo OXW Type1 16 - 321 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YLCC 2.43 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno OXW Type1 14 - 319 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YLCD 2.43 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo OXW Type1 13 - 321 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YLCA 2.43 Inactive DFGout‑None in-out out-out nonTYR APEdihe_aaiii APEdist_oooo OXW Type1 15 - 320 0 None L290V Mitogen-activated protein kinase 6

Ligand: OXW

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 6YLCB
DFGinter None 1 25.0% 6YLCD
DFGout None 1 25.0% 6YLCA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK6 MK06_HUMAN 6YLCB 2.43 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo OXW Type1 16 - 321 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YLCC 2.43 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno OXW Type1 14 - 319 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YLCD 2.43 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo OXW Type1 13 - 321 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YLCA 2.43 Inactive DFGout‑None in-out out-out nonTYR APEdihe_aaiii APEdist_oooo OXW Type1 15 - 320 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens

Ligand: OXW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism