Ligand: OOY

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
None None 2 66.7% 6PMEC
DFGin None 1 33.3% 6PMEB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR NTRK1 NTRK1_HUMAN 6PMEB 3.0 Inactive DFGin‑None in-out out-none TYR APEdihe_niiai APEdist_aaai OOY Type1 499 - 791 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMEA 3.0 Inactive None‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai OOY Type1 500 - 788 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMEC 3.0 Inactive None‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai OOY Type1 500 - 790 0 SEP677 None High affinity nerve growth factor receptor

Ligand: OOY

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
None None 2 66.7% 6PMEC
DFGin None 1 33.3% 6PMEB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR NTRK1 NTRK1_HUMAN 6PMEB 3.0 Inactive DFGin‑None in-out out-none TYR APEdihe_niiai APEdist_aaai OOY Type1 499 - 791 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6PMEA 3.0 Inactive None‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai OOY Type1 500 - 788 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6PMEC 3.0 Inactive None‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai OOY Type1 500 - 790 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens

Ligand: OOY

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism