Ligand: MR9

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2P4IA
DFGout None 1 50.0% 2P4IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TEK TIE2_HUMAN 2P4IA Q02763 838 1117 1124.0 MR9:301 Type2 Inactive DFGout 14.0212 11.7008 BBAminus -136.32, 173.59 -145.12, 114.01 -102.79, 17.92 301.53, 118.36 -72.3, 179.27 in-in in 7.9746 Saltbr-in 2.7259 HRD-in -73.36, -56.61 72.87, 3.4 in-out-in SNCioi out-in ActLoopNT-out 9.8312 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.42, 131.65 APE9-dihe-in -72.54, 124.34 APE8-dihe-in -83.03, 79.81 APE8-rot-na 33.61 APE67-dihe-in -69.75, -16.36 -61.46, -37.5 APE12-dist-na 12.7624 APE11-dist-na 10.1022 APE10-dist-na 12.6782 APE9-dist-in 7.3691 None None None XRAY 2.5 0.248 0.303 A 317.0 252.0 42 27 22 5 [[824, 1094]] 1.0 2p4i TYR_TEK_HUMAN TYR 7.5e-91 310.0 1.0 260.0 260.0 981 982 983 985 987 855 872 876 961 963 962 964.0 1020 1008 1003 1002 1001 1000 999 998 997 903 Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 2P4IB Q02763 836 1117 1124.0 MR9:302 Type2 Inactive DFGout 13.7455 12.0674 None -139.3, -178.13 -154.85, 99.11 -89.78, -137.59 304.87, 121.9 -63.46, 135.48 in-in in 8.2736 Saltbr-in 2.713 HRD-in -82.09, -49.46 82.5, -17.21 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -159.33, 129.69 APE9-dihe-in -65.42, 134.93 APE8-dihe-in -78.37, 56.52 APE8-rot-na 29.79 APE67-dihe-in -64.93, -9.37 -32.69, -53.4 APE12-dist-na 999.0 APE11-dist-na 6.754 APE10-dist-na 8.1485 APE9-dist-out 8.2337 None None None XRAY 2.5 0.248 0.303 B 317.0 258.0 36 27 15 12 [[824, 1094]] 1.0 2p4i TYR_TEK_HUMAN TYR 7.5e-91 310.0 1.0 260.0 260.0 981 982 983 985 987 855 872 876 961 963 962 964.0 1020 1008 1003 1002 1001 1000 999 998 997 903 Angiopoietin-1 receptor

Ligand: MR9

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 2P4IA
DFGout None 1 50.0% 2P4IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TEK TIE2_HUMAN 2P4IA Q02763 838 1117 1124.0 MR9:301 Type2 Inactive DFGout 14.0212 11.7008 BBAminus -136.32, 173.59 -145.12, 114.01 -102.79, 17.92 301.53, 118.36 -72.3, 179.27 in-in in 7.9746 Saltbr-in 2.7259 HRD-in -73.36, -56.61 72.87, 3.4 in-out-in SNCioi out-in ActLoopNT-out 9.8312 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.42, 131.65 APE9-dihe-in -72.54, 124.34 APE8-dihe-in -83.03, 79.81 APE8-rot-na 33.61 APE67-dihe-in -69.75, -16.36 -61.46, -37.5 APE12-dist-na 12.7624 APE11-dist-na 10.1022 APE10-dist-na 12.6782 APE9-dist-in 7.3691 None None None XRAY 2.5 0.248 0.303 A 317.0 252.0 42 27 22 5 [[824, 1094]] 1.0 2p4i Homo sapiens TYR_TEK_HUMAN TYR 7.5e-91 310.0 1.0 260.0 260.0 981 982 983 985 987 855 872 876 961 963 962 964.0 1020 1008 1003 1002 1001 1000 999 998 997 903 Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 2P4IB Q02763 836 1117 1124.0 MR9:302 Type2 Inactive DFGout 13.7455 12.0674 None -139.3, -178.13 -154.85, 99.11 -89.78, -137.59 304.87, 121.9 -63.46, 135.48 in-in in 8.2736 Saltbr-in 2.713 HRD-in -82.09, -49.46 82.5, -17.21 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -159.33, 129.69 APE9-dihe-in -65.42, 134.93 APE8-dihe-in -78.37, 56.52 APE8-rot-na 29.79 APE67-dihe-in -64.93, -9.37 -32.69, -53.4 APE12-dist-na 999.0 APE11-dist-na 6.754 APE10-dist-na 8.1485 APE9-dist-out 8.2337 None None None XRAY 2.5 0.248 0.303 B 317.0 258.0 36 27 15 12 [[824, 1094]] 1.0 2p4i Homo sapiens TYR_TEK_HUMAN TYR 7.5e-91 310.0 1.0 260.0 260.0 981 982 983 985 987 855 872 876 961 963 962 964.0 1020 1008 1003 1002 1001 1000 999 998 997 903 Angiopoietin-1 receptor

Ligand: MR9

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name