Ligand: J0P

Total number of chains: 4
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 50.0% 6E9WA
DFGin BLAminus 2 50.0% 6ED6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC ROCK1 ROCK1_HUMAN 6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1
AGC ROCK1 ROCK1_HUMAN 6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1
AGC ROCK2 ROCK2_HUMAN 6ED6A 2.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 27 - 415 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 6ED6B 2.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno J0P Type1.5_Front 28 - 416 0 None None Rho-associated protein kinase 2

Ligand: J0P

Total number of chains: 5
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% 6E9LA
DFGin ABAminus 2 40.0% 6E9WA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 6E9LA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 18 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus
AGC ROCK1 ROCK1_HUMAN 6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK1 ROCK1_HUMAN 6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6ED6A 2.86 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 27 - 415 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 6ED6B 2.86 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_nnno J0P Type1.5_Front 28 - 416 0 None None Rho-associated protein kinase 2 Homo sapiens

Ligand: J0P

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 6E9LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PRKACA KAPCA_BOVIN 6E9LA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 18 - 351 0 TPO198,SEP339 None cAMP-dependent protein kinase catalytic subunit alpha Bos taurus