CMGC_SRPK2 (SRSF protein kinase 2)

Total number of chains: 8
Active chains: 8
Family: CMGC
Uniprot: SRPK2_HUMAN
Kinase Domain Residues: 81 - 686
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P78362-K1A

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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P78362-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 73 - 688 0 None None SRSF protein kinase 2
AF-P78362-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 73 - 688 0 None None SRSF protein kinase 2
2X7GA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PVB Type1 70 - 688 0 None None SRSF protein kinase 2
5MYVA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
5MYVB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
5MYVC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
5MYVD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2
7ZKXA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 70 - 687 0 None None SRSF protein kinase 2

CMGC_SRPK2 (SRSF protein kinase 2)

Total number of chains: 8
Active chains: 8
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P78362-K1A

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
SRPK2_HUMAN AF-P78362-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 73 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN AF-P78362-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 73 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 2X7GA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PVB Type1 70 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 5MYVA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 5MYVB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 5MYVC 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 5MYVD 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii W4A Type1 68 - 688 0 None None SRSF protein kinase 2 Homo sapiens
SRPK2_HUMAN 7ZKXA 2.06 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXQ Type1 70 - 687 0 None None SRSF protein kinase 2 Homo sapiens

CMGC_SRPK2 (SRSF protein kinase 2)

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism