Ligand: IXQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ZKSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC SRPK1 SRPK1_HUMAN 7ZKSA Q96SB4 67 655 655.0 IXQ:701 Type1 Active DFGin 5.9216 13.8323 BLAminus -124.07, 176.36 61.15, 67.29 -81.69, 19.05 282.89, 92.77 -70.66, -18.4 in-in in 9.6626 Saltbr-in 2.7316 HRD-in -60.32, -44.65 68.64, -2.5 in-in-in SNCiii in-in ActLoopNT-in 2.8691 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.52, 164.81 APE9-dihe-na 71.13, 145.06 APE8-dihe-in -73.4, 143.68 APE8-rot-in 291.25 APE67-dihe-in -76.74, -22.26 -39.85, -46.81 APE12-dist-in 12.6287 APE11-dist-in 10.5346 APE10-dist-in 7.4806 APE9-dist-in 3.0987 None None None XRAY 2.28 0.245 0.29 A 387.0 348.0 22 25 25 0 [[80, 653]] 1.0 7zks CMGC_SRPK1_HUMAN CMGC 1.8e-139 470.0 1.0 301.0 301.0 496 497 498 500 502 109 124 128 210 212 211 213.0 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK2 SRPK2_HUMAN 7ZKXA P78362 70 687 688.0 IXQ:60701 Type1 Active DFGin 6.0787 14.0262 BLAminus -122.16, 177.11 62.56, 63.17 -81.15, 8.95 273.36, 69.73 -50.58, -33.1 in-in in 9.3588 Saltbr-in 2.8117 HRD-in -69.67, -48.62 79.41, -3.75 in-in-in SNCiii in-in ActLoopNT-in 2.7727 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.68, 160.03 APE9-dihe-na 77.15, 136.97 APE8-dihe-in -61.75, 139.32 APE8-rot-in 298.83 APE67-dihe-in -69.39, -20.5 -36.05, -55.19 APE12-dist-in 12.4727 APE11-dist-in 10.2527 APE10-dist-in 7.6473 APE9-dist-in 3.1877 None None None XRAY 2.06 0.181 0.207 A 619.0 339.0 279 25 25 0 [[81, 686]] 1.0 7zkx CMGC_SRPK2_HUMAN CMGC 1.2e-143 483.7 1.0 301.0 301.0 529 530 531 533 535 110 125 129 211 213 212 214.0 566 554 549 548 547 546 545 544 543 167 SRSF protein kinase 2

Ligand: IXQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7ZKSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC SRPK1 SRPK1_HUMAN 7ZKSA Q96SB4 67 655 655.0 IXQ:701 Type1 Active DFGin 5.9216 13.8323 BLAminus -124.07, 176.36 61.15, 67.29 -81.69, 19.05 282.89, 92.77 -70.66, -18.4 in-in in 9.6626 Saltbr-in 2.7316 HRD-in -60.32, -44.65 68.64, -2.5 in-in-in SNCiii in-in ActLoopNT-in 2.8691 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.52, 164.81 APE9-dihe-na 71.13, 145.06 APE8-dihe-in -73.4, 143.68 APE8-rot-in 291.25 APE67-dihe-in -76.74, -22.26 -39.85, -46.81 APE12-dist-in 12.6287 APE11-dist-in 10.5346 APE10-dist-in 7.4806 APE9-dist-in 3.0987 None None None XRAY 2.28 0.245 0.29 A 387.0 348.0 22 25 25 0 [[80, 653]] 1.0 7zks Homo sapiens CMGC_SRPK1_HUMAN CMGC 1.8e-139 470.0 1.0 301.0 301.0 496 497 498 500 502 109 124 128 210 212 211 213.0 533 521 516 515 514 513 512 511 510 166 SRSF protein kinase 1
CMGC SRPK2 SRPK2_HUMAN 7ZKXA P78362 70 687 688.0 IXQ:60701 Type1 Active DFGin 6.0787 14.0262 BLAminus -122.16, 177.11 62.56, 63.17 -81.15, 8.95 273.36, 69.73 -50.58, -33.1 in-in in 9.3588 Saltbr-in 2.8117 HRD-in -69.67, -48.62 79.41, -3.75 in-in-in SNCiii in-in ActLoopNT-in 2.7727 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.68, 160.03 APE9-dihe-na 77.15, 136.97 APE8-dihe-in -61.75, 139.32 APE8-rot-in 298.83 APE67-dihe-in -69.39, -20.5 -36.05, -55.19 APE12-dist-in 12.4727 APE11-dist-in 10.2527 APE10-dist-in 7.6473 APE9-dist-in 3.1877 None None None XRAY 2.06 0.181 0.207 A 619.0 339.0 279 25 25 0 [[81, 686]] 1.0 7zkx Homo sapiens CMGC_SRPK2_HUMAN CMGC 1.2e-143 483.7 1.0 301.0 301.0 529 530 531 533 535 110 125 129 211 213 212 214.0 566 554 549 548 547 546 545 544 543 167 SRSF protein kinase 2

Ligand: IXQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name