Ligand: H6X

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9ET4C

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 9ET4A 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1H6X, A1H6X Type1, Allosteric 1 - 292 0 TPO160 None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET4C 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1H6X, A1H6X Type1, Allosteric 1 - 294 0 TPO160 None Cyclin-dependent kinase 2
TYR FGFR3 FGFR3_HUMAN 7DHLA 2.57 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai H6X Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3

Ligand: H6X

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9ET4C

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 9ET4A 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1H6X, A1H6X Type1, Allosteric 1 - 292 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9ET4C 2.641 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1H6X, A1H6X Type1, Allosteric 1 - 294 0 TPO160 None Cyclin-dependent kinase 2 Homo sapiens
TYR FGFR3 FGFR3_HUMAN 7DHLA 2.57 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai H6X Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3 Homo sapiens

Ligand: H6X

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism