Ligand: EAE

Total number of chains: 6
Active chains: 6
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 6YTDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CLK1 CLK1_HUMAN 6YTDA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 484 0 None V324A Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6YTEC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 484 0 None None Dual specificity protein kinase CLK1
CMGC CLK2 CLK2_HUMAN 6FYIA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 483 0 None None Dual specificity protein kinase CLK2
CMGC CLK3 CLK3_HUMAN 6YTWA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 127 - 481 0 None None Dual specificity protein kinase CLK3
CMGC CLK3 CLK3_HUMAN 6YTWB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 134 - 481 0 None None Dual specificity protein kinase CLK3
CMGC CLK3 CLK3_HUMAN 6YTYA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 127 - 481 0 None A319V Dual specificity protein kinase CLK3

Ligand: EAE

Total number of chains: 6
Active chains: 6
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 6YTDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CLK1 CLK1_HUMAN 6YTDA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 484 0 None V324A Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6YTEC 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 484 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CLK2 CLK2_HUMAN 6FYIA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 148 - 483 0 None None Dual specificity protein kinase CLK2 Homo sapiens
CMGC CLK3 CLK3_HUMAN 6YTWA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 127 - 481 0 None None Dual specificity protein kinase CLK3 Homo sapiens
CMGC CLK3 CLK3_HUMAN 6YTWB 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 134 - 481 0 None None Dual specificity protein kinase CLK3 Homo sapiens
CMGC CLK3 CLK3_HUMAN 6YTYA 1.76 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii EAE Type1 127 - 481 0 None A319V Dual specificity protein kinase CLK3 Homo sapiens

Ligand: EAE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism