Ligand: C0N

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 66.7% 8JF4A
DFGin BLAminus 1 33.3% 8JF3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK AURKA AURKA_HUMAN 8JF4A 2.893 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiii APEdist_nnoo C0N Type1 127 - 389 0 None None Aurora kinase A
TYR SRC SRC_HUMAN 8JF3A 2.846 None DFGin‑BLAminus none-none in-none TYR APEdihe_nnnai APEdist_aaan C0N Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JF3B 2.846 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan C0N Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src

Ligand: C0N

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 66.7% 8JF4A
DFGin BLAminus 1 33.3% 8JF3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK AURKA AURKA_HUMAN 8JF4A 2.893 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiii APEdist_nnoo C0N Type1 127 - 389 0 None None Aurora kinase A Homo sapiens
TYR SRC SRC_HUMAN 8JF3A 2.846 None DFGin‑BLAminus none-none in-none TYR APEdihe_nnnai APEdist_aaan C0N Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 8JF3B 2.846 Inactive DFGin‑None none-none none-none TYR APEdihe_nnnai APEdist_aaan C0N Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens

Ligand: C0N

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism