Ligand: ADE

Total number of chains: 6
Active chains: 5
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 5LVMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PDPK1 PDPK1_HUMAN 5LVMA O15530 76 359 556.0 ADE:401 Type1 Active DFGin 6.5146 14.8576 BLAminus -134.29, -178.73 78.5, 76.19 -107.92, 3.05 284.81, 100.85 -68.49, -15.39 in-in in 8.3988 Saltbr-in 2.9222 HRD-in -74.83, -53.98 76.68, -6.53 in-in-in SNCiii in-in ActLoopNT-in 2.9138 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.77, 160.72 APE9-dihe-na 136.54, -165.87 APE8-dihe-in -131.32, 134.23 APE8-rot-in 298.42 APE67-dihe-in -62.0, -21.56 -53.2, -46.03 APE12-dist-in 7.4265 APE11-dist-in 10.5567 APE10-dist-in 4.9493 APE9-dist-in 3.5336 Y288G,Q292A SEP241 SEP241 XRAY 1.26 0.135 0.155 A 311.0 284.0 0 30 30 0 [[82, 342]] 1.0 5lvm AGC_PDPK1_HUMAN AGC 6.9e-84 286.9 1.0 260.0 260.0 222 223 224 226 228 111 130 134 202 204 203 205.0 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
CAMK CHEK1 CHK1_HUMAN 7BKNA O14757 7 271 476.0 ADE:301 Type1 Active DFGin 6.7151 13.7887 BLAminus -123.22, 178.11 54.82, 98.09 -102.01, 23.12 288.04, 98.46 -58.72, -44.48 in-in in 8.4568 Saltbr-in 2.7209 HRD-in -80.97, -48.58 70.41, 11.52 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.16, 155.63 APE9-dihe-na 150.16, -148.64 APE8-dihe-in -128.29, 117.27 APE8-rot-in 312.17 APE67-dihe-in -60.96, -21.14 -43.64, -55.99 APE12-dist-in 9.3966 APE11-dist-in 11.4738 APE10-dist-in 6.0304 APE9-dist-in 3.7089 None None None XRAY 2.74 0.212 0.28 A 297.0 259.0 6 30 30 0 [[9, 265]] 1.0 7bkn CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2.0 256.0 255.0 147 148 149 151 153 38 55 59 127 129 128 130.0 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 7BJEA O14757 4 270 476.0 ADE:301 Type1 Active DFGin 7.0568 13.5857 BLAminus -121.21, 160.63 79.82, 94.56 -105.52, 22.95 292.15, 82.58 -70.69, -20.75 in-in in 9.1678 Saltbr-in 2.978 HRD-in -77.37, -47.27 75.12, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.8317 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.98, 175.66 APE9-dihe-na 111.76, -150.84 APE8-dihe-in -133.41, 122.32 APE8-rot-in 300.48 APE67-dihe-in -64.02, -19.73 -50.61, -46.69 APE12-dist-in 8.9332 APE11-dist-in 11.7376 APE10-dist-in 6.194 APE9-dist-in 3.3802 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297.0 259.0 8 30 30 0 [[9, 265]] 1.0 7bje CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2.0 256.0 255.0 147 148 149 151 153 38 55 59 127 129 128 130.0 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
STE STK24 STK24_HUMAN 3A7IA Q9Y6E0 25 311 443.0 ADE:60500 Type1 Active DFGin 6.7665 14.6665 BLAminus -139.7, 169.86 69.51, 79.83 -97.21, 20.61 291.41, 90.13 -61.26, -25.52 in-in in 8.5773 Saltbr-in 2.5658 HRD-in -67.58, -47.33 70.78, -0.73 in-in-in SNCiii in-in ActLoopNT-in 2.8297 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.32, 160.03 APE9-dihe-na 126.67, -163.45 APE8-dihe-in -118.33, 123.78 APE8-rot-in 300.92 APE67-dihe-in -61.68, -23.93 -38.56, -53.0 APE12-dist-in 8.2566 APE11-dist-in 10.9234 APE10-dist-in 5.1055 APE9-dist-in 3.3212 None TPO190 TPO190 XRAY 1.45 0.194 0.217 A 303.0 287.0 0 28 28 0 [[36, 286]] 1.0 3a7i STE_STK24_HUMAN STE 3.6e-100 340.5 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24
TKL ACVR2B AVR2B_HUMAN 2QLUA Q13705 190 484 512.0 ADE:60488 Type1 Active DFGin 7.2815 13.9189 BLAminus -143.64, 166.04 72.05, 78.25 -102.89, 27.27 300.97, 123.79 -72.21, -17.92 in-in in 7.9453 Saltbr-in 3.516 HRD-in -60.9, -56.13 82.96, -12.74 in-in-in SNCiii in-in ActLoopNT-in 2.9761 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.21, -18.6 APE9-dihe-na -82.16, 165.01 APE8-dihe-in -51.41, 126.96 APE8-rot-in 299.08 APE67-dihe-in -55.0, -24.76 -57.11, -46.21 APE12-dist-in 11.0378 APE11-dist-in 12.1003 APE10-dist-in 6.1131 APE9-dist-in 3.5482 None None None XRAY 2.0 0.219 0.283 A 314.0 295.0 0 30 30 0 [[190, 480]] 1.0 2qlu TKL_ACVR2B_HUMAN TKL 1.3e-76 263.6 2.0 265.0 264.0 338 339 340 342 344 217 230 234 318 320 319 321.0 385 368 363 362 361 360 359 358 357 266 Activin receptor type-2B
TYR RET RET_HUMAN 6NJAA P07949 705 1013 1114.0 ADE:61101 Type1 Inactive DFGin 6.799 13.8776 BLAminus -137.14, 177.68 65.42, 76.1 -98.1, 14.96 280.4, 84.03 -65.23, -23.92 in-in in 7.169 Saltbr-in 2.8905 HRD-in -73.14, -47.89 82.54, -25.42 in-in-out SNCiio in-out ActLoopNT-in 2.9426 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.72, 15.0 APE9-dihe-in -85.67, 136.78 APE8-dihe-in -51.46, 130.0 APE8-rot-na 328.83 APE67-dihe-in -73.82, -7.14 -46.66, -43.11 APE12-dist-na 13.7528 APE11-dist-na 9.3529 APE10-dist-na 7.7596 APE9-dist-in 5.4577 None PTR900,PTR905 PTR900,PTR905 XRAY 1.92 0.188 0.234 A 314.0 289.0 20 30 30 0 [[724, 1007]] 1.0 6nja TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: ADE

Total number of chains: 9
Active chains: 7
Total number of genes: 8
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 9 100.0% 5LVMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6Y05A P25321 8 351 351.0 ADE:60401 Type1 Active DFGin 6.2038 13.15 BLAminus -122.62, 176.1 60.39, 98.08 -109.84, 29.54 293.58, 72.67 -62.59, -23.96 in-in in 8.9695 Saltbr-in 2.6495 HRD-in -91.46, -52.85 71.13, 13.97 in-in-in SNCiii in-in ActLoopNT-in 2.944 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.05, 162.66 APE9-dihe-na 130.15, -156.07 APE8-dihe-in -123.62, 136.19 APE8-rot-in 301.3 APE67-dihe-in -59.67, -24.1 -52.64, -47.85 APE12-dist-in 8.102 APE11-dist-in 11.5295 APE10-dist-in 5.9277 APE9-dist-in 3.5458 None TPO198,SEP339 TPO198,SEP339 XRAY 1.7 0.178 0.205 A 353.0 344.0 0 25 25 0 [[44, 298]] 1.0 6y05 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PDPK1 PDPK1_HUMAN 5LVMA O15530 76 359 556.0 ADE:401 Type1 Active DFGin 6.5146 14.8576 BLAminus -134.29, -178.73 78.5, 76.19 -107.92, 3.05 284.81, 100.85 -68.49, -15.39 in-in in 8.3988 Saltbr-in 2.9222 HRD-in -74.83, -53.98 76.68, -6.53 in-in-in SNCiii in-in ActLoopNT-in 2.9138 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.77, 160.72 APE9-dihe-na 136.54, -165.87 APE8-dihe-in -131.32, 134.23 APE8-rot-in 298.42 APE67-dihe-in -62.0, -21.56 -53.2, -46.03 APE12-dist-in 7.4265 APE11-dist-in 10.5567 APE10-dist-in 4.9493 APE9-dist-in 3.5336 Y288G,Q292A SEP241 SEP241 XRAY 1.26 0.135 0.155 A 311.0 284.0 0 30 30 0 [[82, 342]] 1.0 5lvm Homo sapiens AGC_PDPK1_HUMAN AGC 6.9e-84 286.9 1.0 260.0 260.0 222 223 224 226 228 111 130 134 202 204 203 205.0 264 252 247 246 245 244 243 242 241 160 3-phosphoinositide-dependent protein kinase 1
CAMK CHEK1 CHK1_HUMAN 7BKNA O14757 7 271 476.0 ADE:301 Type1 Active DFGin 6.7151 13.7887 BLAminus -123.22, 178.11 54.82, 98.09 -102.01, 23.12 288.04, 98.46 -58.72, -44.48 in-in in 8.4568 Saltbr-in 2.7209 HRD-in -80.97, -48.58 70.41, 11.52 in-in-in SNCiii in-in ActLoopNT-in 2.978 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.16, 155.63 APE9-dihe-na 150.16, -148.64 APE8-dihe-in -128.29, 117.27 APE8-rot-in 312.17 APE67-dihe-in -60.96, -21.14 -43.64, -55.99 APE12-dist-in 9.3966 APE11-dist-in 11.4738 APE10-dist-in 6.0304 APE9-dist-in 3.7089 None None None XRAY 2.74 0.212 0.28 A 297.0 259.0 6 30 30 0 [[9, 265]] 1.0 7bkn Homo sapiens CAMK_CHEK1_HUMAN CAMK 2.9e-71 245.7 2.0 256.0 255.0 147 148 149 151 153 38 55 59 127 129 128 130.0 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
CAMK CHEK1 CHK1_HUMAN 7BJEA O14757 4 270 476.0 ADE:301 Type1 Active DFGin 7.0568 13.5857 BLAminus -121.21, 160.63 79.82, 94.56 -105.52, 22.95 292.15, 82.58 -70.69, -20.75 in-in in 9.1678 Saltbr-in 2.978 HRD-in -77.37, -47.27 75.12, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.8317 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.98, 175.66 APE9-dihe-na 111.76, -150.84 APE8-dihe-in -133.41, 122.32 APE8-rot-in 300.48 APE67-dihe-in -64.02, -19.73 -50.61, -46.69 APE12-dist-in 8.9332 APE11-dist-in 11.7376 APE10-dist-in 6.194 APE9-dist-in 3.3802 N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S None None XRAY 1.8 0.173 0.199 A 297.0 259.0 8 30 30 0 [[9, 265]] 1.0 7bje Homo sapiens CAMK_CHEK1_HUMAN CAMK 4.8e-69 238.4 2.0 256.0 255.0 147 148 149 151 153 38 55 59 127 129 128 130.0 190 177 172 171 170 169 168 167 166 85 Serine/threonine-protein kinase Chk1
STE STK24 STK24_HUMAN 3A7IA Q9Y6E0 25 311 443.0 ADE:60500 Type1 Active DFGin 6.7665 14.6665 BLAminus -139.7, 169.86 69.51, 79.83 -97.21, 20.61 291.41, 90.13 -61.26, -25.52 in-in in 8.5773 Saltbr-in 2.5658 HRD-in -67.58, -47.33 70.78, -0.73 in-in-in SNCiii in-in ActLoopNT-in 2.8297 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.32, 160.03 APE9-dihe-na 126.67, -163.45 APE8-dihe-in -118.33, 123.78 APE8-rot-in 300.92 APE67-dihe-in -61.68, -23.93 -38.56, -53.0 APE12-dist-in 8.2566 APE11-dist-in 10.9234 APE10-dist-in 5.1055 APE9-dist-in 3.3212 None TPO190 TPO190 XRAY 1.45 0.194 0.217 A 303.0 287.0 0 28 28 0 [[36, 286]] 1.0 3a7i Homo sapiens STE_STK24_HUMAN STE 3.6e-100 340.5 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24
TKL ACVR2B AVR2B_HUMAN 2QLUA Q13705 190 484 512.0 ADE:60488 Type1 Active DFGin 7.2815 13.9189 BLAminus -143.64, 166.04 72.05, 78.25 -102.89, 27.27 300.97, 123.79 -72.21, -17.92 in-in in 7.9453 Saltbr-in 3.516 HRD-in -60.9, -56.13 82.96, -12.74 in-in-in SNCiii in-in ActLoopNT-in 2.9761 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.21, -18.6 APE9-dihe-na -82.16, 165.01 APE8-dihe-in -51.41, 126.96 APE8-rot-in 299.08 APE67-dihe-in -55.0, -24.76 -57.11, -46.21 APE12-dist-in 11.0378 APE11-dist-in 12.1003 APE10-dist-in 6.1131 APE9-dist-in 3.5482 None None None XRAY 2.0 0.219 0.283 A 314.0 295.0 0 30 30 0 [[190, 480]] 1.0 2qlu Homo sapiens TKL_ACVR2B_HUMAN TKL 1.3e-76 263.6 2.0 265.0 264.0 338 339 340 342 344 217 230 234 318 320 319 321.0 385 368 363 362 361 360 359 358 357 266 Activin receptor type-2B
TYR RET RET_HUMAN 6NJAA P07949 705 1013 1114.0 ADE:61101 Type1 Inactive DFGin 6.799 13.8776 BLAminus -137.14, 177.68 65.42, 76.1 -98.1, 14.96 280.4, 84.03 -65.23, -23.92 in-in in 7.169 Saltbr-in 2.8905 HRD-in -73.14, -47.89 82.54, -25.42 in-in-out SNCiio in-out ActLoopNT-in 2.9426 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -111.72, 15.0 APE9-dihe-in -85.67, 136.78 APE8-dihe-in -51.46, 130.0 APE8-rot-na 328.83 APE67-dihe-in -73.82, -7.14 -46.66, -43.11 APE12-dist-na 13.7528 APE11-dist-na 9.3529 APE10-dist-na 7.7596 APE9-dist-in 5.4577 None PTR900,PTR905 PTR900,PTR905 XRAY 1.92 0.188 0.234 A 314.0 289.0 20 30 30 0 [[724, 1007]] 1.0 6nja Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
AGC PRKCI KPCI_MOUSE 4DC2A Q62074 248 586 595.0 ADE:60601 Type1 None DFGin 5.5144 11.5945 BLAminus -116.21, -173.67 60.87, 97.17 -103.56, 4.24 303.35, 138.78 -42.92, -43.52 in-none in 9.0991 Saltbr-none 999.0 HRD-in -77.29, -48.77 70.59, -5.86 none-in-in SNCnii in-in ActLoopNT-in 2.7891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.58, 165.79 APE9-dihe-na 134.32, -165.14 APE8-dihe-in -104.82, 125.13 APE8-rot-in 306.69 APE67-dihe-in -51.64, -27.58 -50.63, -43.23 APE12-dist-in 8.6109 APE11-dist-in 11.6064 APE10-dist-in 6.2195 APE9-dist-in 3.6877 None TPO563 TPO563 XRAY 2.4 0.176 0.241 A 396.0 329.0 10 28 28 0 [[253, 521]] 1.0 4dc2 Mus musculus AGC_PRKCI_MOUSE AGC 1.2e-94 322.3 1.0 260.0 260.0 394 395 396 398 400 282 301 305 374 376 375 377.0 434 422 417 416 415 414 413 412 411 332 Protein kinase C iota type
CMGC SKY1 SKY1_YEAST 1Q8YB Q03656 146 737 742.0 ADE:60900 Type1 Active DFGin 5.7056 12.734 BLAminus -114.79, 174.03 53.01, 83.35 -90.33, 21.72 295.68, 19.7 -60.04, -25.8 in-in in 8.7993 Saltbr-in 2.803 HRD-in -73.75, -48.02 75.59, -7.87 in-in-in SNCiii in-in ActLoopNT-in 2.8616 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.89, 171.09 APE9-dihe-na 62.9, 152.57 APE8-dihe-in -91.8, 140.89 APE8-rot-in 291.31 APE67-dihe-in -54.87, -26.09 -16.43, -79.7 APE12-dist-in 12.5312 APE11-dist-in 10.5145 APE10-dist-in 7.7607 APE9-dist-in 3.0126 None None None XRAY 2.05 0.209 0.244 B 373.0 357.0 3 25 25 0 [[158, 706]] 1.0 1q8y Saccharomyces cerevisiae CMGC_SKY1_YEAST CMGC 8.8e-100 339.7 1.0 301.0 301.0 549 550 551 553 555 187 202 206 291 293 292 294.0 586 574 569 568 567 566 565 564 563 247 Serine/threonine-protein kinase SKY1

Ligand: ADE

Total number of chains: 3
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6Y05A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6Y05A P25321 8 351 351.0 ADE:60401 Type1 Active DFGin 6.2038 13.15 BLAminus -122.62, 176.1 60.39, 98.08 -109.84, 29.54 293.58, 72.67 -62.59, -23.96 in-in in 8.9695 Saltbr-in 2.6495 HRD-in -91.46, -52.85 71.13, 13.97 in-in-in SNCiii in-in ActLoopNT-in 2.944 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.05, 162.66 APE9-dihe-na 130.15, -156.07 APE8-dihe-in -123.62, 136.19 APE8-rot-in 301.3 APE67-dihe-in -59.67, -24.1 -52.64, -47.85 APE12-dist-in 8.102 APE11-dist-in 11.5295 APE10-dist-in 5.9277 APE9-dist-in 3.5458 None TPO198,SEP339 TPO198,SEP339 XRAY 1.7 0.178 0.205 A 353.0 344.0 0 25 25 0 [[44, 298]] 1.0 6y05 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKCI KPCI_MOUSE 4DC2A Q62074 248 586 595.0 ADE:60601 Type1 None DFGin 5.5144 11.5945 BLAminus -116.21, -173.67 60.87, 97.17 -103.56, 4.24 303.35, 138.78 -42.92, -43.52 in-none in 9.0991 Saltbr-none 999.0 HRD-in -77.29, -48.77 70.59, -5.86 none-in-in SNCnii in-in ActLoopNT-in 2.7891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -163.58, 165.79 APE9-dihe-na 134.32, -165.14 APE8-dihe-in -104.82, 125.13 APE8-rot-in 306.69 APE67-dihe-in -51.64, -27.58 -50.63, -43.23 APE12-dist-in 8.6109 APE11-dist-in 11.6064 APE10-dist-in 6.2195 APE9-dist-in 3.6877 None TPO563 TPO563 XRAY 2.4 0.176 0.241 A 396.0 329.0 10 28 28 0 [[253, 521]] 1.0 4dc2 Mus musculus AGC_PRKCI_MOUSE AGC 1.2e-94 322.3 1.0 260.0 260.0 394 395 396 398 400 282 301 305 374 376 375 377.0 434 422 417 416 415 414 413 412 411 332 Protein kinase C iota type
CMGC SKY1 SKY1_YEAST 1Q8YB Q03656 146 737 742.0 ADE:60900 Type1 Active DFGin 5.7056 12.734 BLAminus -114.79, 174.03 53.01, 83.35 -90.33, 21.72 295.68, 19.7 -60.04, -25.8 in-in in 8.7993 Saltbr-in 2.803 HRD-in -73.75, -48.02 75.59, -7.87 in-in-in SNCiii in-in ActLoopNT-in 2.8616 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.89, 171.09 APE9-dihe-na 62.9, 152.57 APE8-dihe-in -91.8, 140.89 APE8-rot-in 291.31 APE67-dihe-in -54.87, -26.09 -16.43, -79.7 APE12-dist-in 12.5312 APE11-dist-in 10.5145 APE10-dist-in 7.7607 APE9-dist-in 3.0126 None None None XRAY 2.05 0.209 0.244 B 373.0 357.0 3 25 25 0 [[158, 706]] 1.0 1q8y Saccharomyces cerevisiae CMGC_SKY1_YEAST CMGC 8.8e-100 339.7 1.0 301.0 301.0 549 550 551 553 555 187 202 206 291 293 292 294.0 586 574 569 568 567 566 565 564 563 247 Serine/threonine-protein kinase SKY1