Ligand: A1IMS

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9DF3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9DF2A P00533 701 1004 1210.0 A1IMS:61101 Type1.5_Back Active DFGin 6.1776 13.8194 BLAminus -138.62, 178.98 67.62, 97.78 -114.22, 32.37 297.28, 88.95 -71.37, -22.63 in-in in 8.2649 Saltbr-in 2.6866 HRD-in -67.48, -51.99 72.72, 4.57 in-in-in SNCiii in-in ActLoopNT-in 2.9431 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.21, 135.87 APE9-dihe-in -144.97, 152.75 APE8-dihe-in -81.03, 89.7 APE8-rot-na 33.51 APE67-dihe-in -75.91, -6.34 -54.41, -42.45 APE12-dist-na 12.5625 APE11-dist-na 9.691 APE10-dist-na 10.5294 APE9-dist-in 6.3481 V948R None None XRAY 2.5 0.199 0.245 A 333.0 299.0 5 30 30 0 [[712, 970]] 1.0 9df2 TYR_EGFR_HUMAN TYR 6.3e-86 293.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF3A P00533 701 1022 1210.0 A1IMS:61101 Type1.5_Back Active DFGin 6.12 14.0795 BLAminus -133.91, -175.29 63.5, 92.21 -102.95, 27.03 288.2, 89.06 -60.61, -32.74 in-in in 8.4492 Saltbr-in 2.7787 HRD-in -72.11, -45.74 69.04, 1.04 in-in-in SNCiii in-in ActLoopNT-in 2.8534 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.71, 138.45 APE9-dihe-in -139.83, 153.3 APE8-dihe-in -82.59, 82.51 APE8-rot-na 33.21 APE67-dihe-in -70.96, -9.32 -51.24, -45.73 APE12-dist-na 12.3194 APE11-dist-na 9.4652 APE10-dist-na 10.0866 APE9-dist-in 6.4766 V948R None None XRAY 1.68 0.172 0.2 A 333.0 308.0 4 30 30 0 [[712, 970]] 1.0 9df3 TYR_EGFR_HUMAN TYR 5.8e-86 294.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL7A P00533 702 1019 1210.0 A1IMS:62001 Type1.5_Back Active DFGin 6.1544 14.0797 BLAminus -129.2, -177.57 64.25, 98.42 -114.09, 41.48 295.01, 81.54 -76.03, -38.0 in-in in 8.4238 Saltbr-in 2.7177 HRD-in -64.01, -43.17 64.53, -6.85 in-in-in SNCiii in-in ActLoopNT-in 2.9536 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.93, 136.43 APE9-dihe-in -141.98, 154.21 APE8-dihe-in -82.6, 89.72 APE8-rot-na 31.06 APE67-dihe-in -63.89, -13.13 -49.96, -51.09 APE12-dist-na 12.3925 APE11-dist-na 9.6441 APE10-dist-na 10.0448 APE9-dist-in 6.4678 V948R None None XRAY 1.878 0.269 0.287 A 338.0 297.0 7 30 30 0 [[712, 970]] 1.0 9gl7 TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IMS

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9DF3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9DF2A P00533 701 1004 1210.0 A1IMS:61101 Type1.5_Back Active DFGin 6.1776 13.8194 BLAminus -138.62, 178.98 67.62, 97.78 -114.22, 32.37 297.28, 88.95 -71.37, -22.63 in-in in 8.2649 Saltbr-in 2.6866 HRD-in -67.48, -51.99 72.72, 4.57 in-in-in SNCiii in-in ActLoopNT-in 2.9431 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.21, 135.87 APE9-dihe-in -144.97, 152.75 APE8-dihe-in -81.03, 89.7 APE8-rot-na 33.51 APE67-dihe-in -75.91, -6.34 -54.41, -42.45 APE12-dist-na 12.5625 APE11-dist-na 9.691 APE10-dist-na 10.5294 APE9-dist-in 6.3481 V948R None None XRAY 2.5 0.199 0.245 A 333.0 299.0 5 30 30 0 [[712, 970]] 1.0 9df2 Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-86 293.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF3A P00533 701 1022 1210.0 A1IMS:61101 Type1.5_Back Active DFGin 6.12 14.0795 BLAminus -133.91, -175.29 63.5, 92.21 -102.95, 27.03 288.2, 89.06 -60.61, -32.74 in-in in 8.4492 Saltbr-in 2.7787 HRD-in -72.11, -45.74 69.04, 1.04 in-in-in SNCiii in-in ActLoopNT-in 2.8534 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.71, 138.45 APE9-dihe-in -139.83, 153.3 APE8-dihe-in -82.59, 82.51 APE8-rot-na 33.21 APE67-dihe-in -70.96, -9.32 -51.24, -45.73 APE12-dist-na 12.3194 APE11-dist-na 9.4652 APE10-dist-na 10.0866 APE9-dist-in 6.4766 V948R None None XRAY 1.68 0.172 0.2 A 333.0 308.0 4 30 30 0 [[712, 970]] 1.0 9df3 Homo sapiens TYR_EGFR_HUMAN TYR 5.8e-86 294.1 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL7A P00533 702 1019 1210.0 A1IMS:62001 Type1.5_Back Active DFGin 6.1544 14.0797 BLAminus -129.2, -177.57 64.25, 98.42 -114.09, 41.48 295.01, 81.54 -76.03, -38.0 in-in in 8.4238 Saltbr-in 2.7177 HRD-in -64.01, -43.17 64.53, -6.85 in-in-in SNCiii in-in ActLoopNT-in 2.9536 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.93, 136.43 APE9-dihe-in -141.98, 154.21 APE8-dihe-in -82.6, 89.72 APE8-rot-na 31.06 APE67-dihe-in -63.89, -13.13 -49.96, -51.09 APE12-dist-na 12.3925 APE11-dist-na 9.6441 APE10-dist-na 10.0448 APE9-dist-in 6.4678 V948R None None XRAY 1.878 0.269 0.287 A 338.0 297.0 7 30 30 0 [[712, 970]] 1.0 9gl7 Homo sapiens TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IMS

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name